View source for Non-specific intestinal inflammations

Among the '''nonspecific intestinal inflammations'''' <ref>{{Cite|type = web| surname1 = Šerclová| name1 = Z| collective = yes| url = https://www.cgs-cls.cz/wp-content/uploads/2017/02/06.pdf
| source_name = Recommended procedures for surgical treatment of patients with non-specific intestinal inflammation - Part 1: preoperative preparation
| year = 2015
| cited = 2019-06-07}}</ref> include [[Crohn's disease]] (''ileitis terminalis'') and [[ulcerative colitis]] (''proctocolitis idiopathica''). These are chronic inflammatory diseases of the digestive tract, which are often accompanied by abundant extraintestinal symptoms. Both diseases begin in childhood or during adolescence and their etiology is unclear. The incidence and prevalence of non-specific intestinal inflammation has been increasing in recent years, 20-30% of patients are children under the age of 18.<ref name="KlinPed2012">{{Cite| type = book| surname1 = Lebl| name1 = J| surname2 = Janda
| name2 = J| surname3 = Pohunek| name3 = P| collective = yes| title = Clinical Pediatrics| edition = 1| publisher = Galen| year = 2012| pages = 311-318| range = 698| isbn = 978-80-7262-772-1}}</ref>
[[File:Crohn's disease ulcerative colitis.png|thumb|Crohn's disease vs. ulcerative colitis]]
;Crohn's disease
It is a chronic non-specific inflammation of the small or large intestine (or any part of the GIT). It is segmental or multisegmental, transmural, in typical cases granulomatous inflammation.
;Ulcerative colitis
Non-specific hemorrhagic-catarrhal or ulcerative inflammation of the anus and the adjacent part (or the entire colon) with an abrupt or chronically exacerbating course.
;Indeterminate (undetermined) colitis
It is an inflammation of the large intestine with characteristic overlapping features of Crohn's disease and ulcerative colitis or with various atypical signs that make it impossible to clearly classify the disease.<ref name="KlinPed2012" />
{| class="wikitable"
! !!Crohn's disease!!ulcerative colitis<ref>{{Cite |type = book|surname1 = Muntau|firstname1 = Ania Carolina|collective = no|title = Pediatrics|edition = 4|place = Prague|publisher = Grada|year = 2009|pages = 372- 377|isbn = 978-80-247-2525-3}}</ref><ref name="KlinPed2012" />
|-
|localization||the entire digestive tract, most often the terminal ileum||rectum and colon
|-
|mode of disability||segmental (alternation of inflamed and unaffected sections)||continuous progress in the oral direction
|-
|Abdominal X-ray||thickening of the intestinal wall, stenosis||extinct haustration
|-
|[[endoscopy]]||discontinuous involvement, focal aphthae, linear ulcers||hemorrhagic mucosa, diffuse inflammation, pseudopolyps
|-
|histology||inflammation of all layers of the intestinal wall (transmural)||inflammation of the mucous membrane and submucosa
|-
| ||typical epithelioid granulomas, lymphocytic infiltrates||cryptitis, crypt [[abscesses]]
|-
|clinical picture||abdominal pain, diarrhea - rarely with blood||bloody diarrhea with tenesmus
|-
| ||fever, weight loss, anorexia, growth retardation||
|-
|complications||formation of fistulas, stenoses and abscesses||increased risk of cancer
|}{{Details|Crohn's Disease}}{{Details|Ulcerative colitis}}<noinclude>

==Links==
===Related Articles===
*[[Autoimmune diseases]] • [[Diarrheal diseases (signpost)]] • [[Pseudomembranous enterocolitis]]
===External links===
*{{Cite | type=web | url=https://www.cgs-cls.cz/informace-pro-pacienty/nespecificke-strevni-zanety/| surname1=Zádorová | name1=Zdena | source_name=Czech Gastroenterological Society | subtitle=Nonspecific intestinal inflammation | year=2007 | revision_date=2009-01-23 | cited=2010-05-02}}
===References===
<references /></noinclude>

[[Category:Gastroenterology]]
[[Category:Pathophysiology]]
[[Category:Pathology]]
[[Category:Paediatrics]]
[[Category:Internal Medicine]]
[[Category:Immunology]]