View source for Vitamin B9 (Folic acid)

<!----------------------------------------------------------------------------------------------------------------
*  INSERTED ARTICLE
*  Warning – this article is used in other articles where it is inserted. If you are changing this article, you are changing other articles at the same moment. Please, be careful when you are editing it:
*    1. Do not remove commands <noinclude> </noinclude>. These commands usually mark parts which should not be used in other articles, when this article is being inserted. 
*    2. Do not change level of headings. 
*    3. Great expansion or removing of the text of the article can change the meaning of other articles. You can discuss all these changes on the discussion page of this article.
* All the articles, where this article is inserted can be found in ''Toolbox'' → ''What links here''. 
*
* Please, do not remove this comment. If you are not sure, you can contact our [[WikiLectures:Editorial board | editorial board]].
*
* This warning note is automatically inserted by inserting the template {{subst:Inserted article}}.
-------------------------------------------------------------------------------------------------------------->__NOTOC__
[[File:Folic acid.png|thumb|Vitamin B9 structure]]
Folic acid also is known as vitamin B<sub>9</sub>, folate or folacin . Includes a group of compounds: Folic Acid (contains pterin, p-aminobenzoic acid and glutamic ) and folic acid. Along with vitamin B<sub>12</sub> is essential for the formation of nucleic acids and thus for synthesis of DNA , participate in the transfer radicals and in all processes of cell division , it is important for cell division and tissue with high mitotic activity.Absorbed in the proximal parts of the small intestine and when excess it is excreted in the urine.
=== Source ===
Liver, yeast, green leafy vegetables, as well as whole grain cereals, meat, milk, eggs and legumes.
The recommended daily adult dose: 400mg. In pregnancy, 600mg for prevention of congenital malformations (mainly cleft neural tube).
=== Deficit ===
Deficiency of vitamin B<sub>9</sub> occurs in low supply, absorption or increased need during pregnancy. There is a megaloblastic anaemia , which is characterized by the presence of abnormal precursors of red blood cells in the bone marrow. Compared with normal cells are cells arising from these abnormal precursors of different shape, larger size, reduced viability and reduced ability to transport oxygen .
Along with the lack of iron is its lack of a significant cause of anaemia in developing countries. Deficiency during pregnancy causes spina neural tube in the fetus.
* Laboratory evaluation: serum levels of folate, total homocysteine (increases in the absence, also in the absence of vitamin B<sub>12</sub>)
=== Surplus ===
High intake of folic acid can mask vitamin B<sub>12</sub> , so the upper limit of the daily recommended intake of up to 1000 mg / day.

<big>'''Folate deficiency:'''</big> {{Video | url=https://youtu.be/fgvMMx7A5L0?t=292}}


<big>'''Folate deficiency 2:'''</big> {{Video | url=https://youtu.be/T5zevdrQBDw?t=393}}


<noinclude>
== Links ==
*[[ws:Kyselina listová]]
=== Related articles ===
* [[Fat Soluble Vitamins]]
* [[Water Soluble Vitamins]]
=== Bibliography ===
* {{Cite
| type = book
| surname1 = Bencko
| name1 = Vladimir
| others = yes
| title = Hygiene and epidemiology
| subtitle = selected chapters
| edition = 2
| location = Prague
| year = 2008
| isbn = 80-246-0793-X
}}
</noinclude>

[[Category:Inserted articles]]
[[Category:Hygiene]]
[[Category:Epidemiology]]