Specificity

Specificity is the probability of a negative result in healthy patients b/b+d. The specificity of a test reflects on the ability of a test to identify true negatives.

${\begin{aligned}{\text{specificity}}&={\frac {\text{number of true negatives}}{{\text{number of true negatives}}+{\text{number of false positives}}}}\\\\&={\text{probability of a negative test given that the patient is well}}\end{aligned}}$

For example, if he had a mammography screening for breast cancer with 100% specificity, it would mean that all women without breast cancer that underwent screening tested negative. We have a group of 4 women - Lucy, Jane, Cathie and Lenka. has breast cancer. Lucy has breast cancer. All women undergo the screening mammography. It detects Lucy and Jane as positive. Lucy is really positive. Jane is a false positive. Cathie and Lenka are actually negative. Nobody is falsely negative. When you enter the values into the formula above, we find that the test showed about 67% specificity (specificity = 0.67). One woman with no tumor was identified as positive (we have one woman falsely positive).

Test	Disease +	Healthy-	Total
+	a	b	a+b
-	c	d	c+d
Total	a+c	b+d	n

 For more information see Requirements at Examination Methods.

Links

Related Article

• Sensitivity

Bibliography

• BENCKO, Vladimír. Epidemiologie, výukové texty pro studenty. 2nd edition. Karolinum, 2002. ISBN 80-246-0383-7..

• BENCKO, Vladimír. Biomedicínská statistika. 1st edition. Karolinum, 2003. ISBN 80-246-0763-8.

• KUPKA, Karel. Nukleární medicína. 1st edition. Karolinum, 2007. ISBN 978-80-903584-9-2.