Allergic skin manifestations: Difference between revisions
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=== [[Allergic contact dermatitis]]=== | === [[Allergic contact dermatitis]]=== | ||
* itchy eczematous deposits at the points of contact with the allergen (nickel and other metals, topical drugs, perfumes, preservatives and rubber - | * itchy eczematous deposits at the points of contact with the allergen (nickel and other metals, topical drugs, perfumes, preservatives and rubber - thiomersal) | ||
* [[delayed type hypersensitivity reaction]] (type IV), mediated by hapten-specific T cells | * [[delayed type hypersensitivity reaction|delayed-type hypersensitivity reaction]] (type IV), mediated by hapten-specific T cells | ||
* diagnostics - epicutaneous tests. | * diagnostics - epicutaneous tests. | ||
Revision as of 18:04, 9 April 2022
Allergic skin manifestations include: urticaria caused by immunological mechanisms and angioedema, allergic contact dermatitis and atopic dermatitis.
Urticaria induced by immunological mechanisms
- Anaphylactic type of hypersensitivity (IgE-mediated allergy; type I) - short-term acute reaction to food, medication or contact allergens.
- Immunocomplex type of hypersensitivity (non-IgE mediated allergy; type III) - serum disease type reaction after treatment with penicillin or after application of foreign organ extracts containing proteins (foreign sera, hormones) and urticarial vasculitis.
- Autoimmune mechanisms (type II; autoantibodies, especially IgG1 and IgG3 classes against the FcεRIα receptor of mast cells, or against IgE immunoglobulins) - chronic urticaria, sometimes in association with autoimmune thyroid disease, dermatomyositis or SLE.
Angioedema
- Deficiency in the complement system (inhibitor of the C1 component of complement) - angioedema (hereditary, acquired and arising as an adverse effect of drugs from the group of ACE inhibitors).
Allergic contact dermatitis
- itchy eczematous deposits at the points of contact with the allergen (nickel and other metals, topical drugs, perfumes, preservatives and rubber - thiomersal)
- delayed-type hypersensitivity reaction (type IV), mediated by hapten-specific T cells
- diagnostics - epicutaneous tests.
Atopic eczema
- chronic, recurrent, itchy skin disease.
Links
Related articles
Extern links
Literature
References
- VIKTORINOVÁ, M. Kopřivky vyvolané imunologickými mechanizmy. Dermatologie pro praxi [online]. 2008, roč. 2, vol. 5-6, s. 218-222, dostupné také z <https://www.dermatologiepropraxi.cz/pdfs/der/2008/05/02.pdf>.
