Acrosome reaction: Difference between revisions
(Created page with "__TOC__ preview|390px|right|Acrosome reaction '''Acrosome reaction'''' (acrosomal reaction) is the release of enzymes from the acroso...") |
|||
| Line 19: | Line 19: | ||
| type = book | | type = book | ||
| isbn = 978-80-247-2640-3 | | isbn = 978-80-247-2640-3 | ||
| | | surname1 = Sadler | ||
| | | name1 = Thomas, W | ||
| | | surname2 = Sinha | ||
| | | name2 = M.D | ||
| title = Langman's Medical Embryology | | title = Langman's Medical Embryology | ||
| subtitle = Textbook for medical students and general nursing and midwifery students | | subtitle = Textbook for medical students and general nursing and midwifery students | ||
| Line 29: | Line 29: | ||
| publisher = Grada | | publisher = Grada | ||
| year = 2011 | | year = 2011 | ||
| | | pages = 414 | ||
}} | }} | ||
* {{Cite | * {{Cite | ||
| type = book | | type = book | ||
| isbn = 978-80-246-1860-9 | | isbn = 978-80-246-1860-9 | ||
| | | surname1 = Vajner | ||
| | | name1 = Luděk | ||
| | | surname2 = Uhlík | ||
| | | name2 = Jiří | ||
| | | surname3 = Konrádová | ||
| | | name3 = Václava | ||
| title = Medical histology. 1, Cytology and general histology | | title = Medical histology. 1, Cytology and general histology | ||
| edition = 1 | | edition = 1 | ||
| Line 45: | Line 45: | ||
| publisher = Karolinum | | publisher = Karolinum | ||
| year = 2010 | | year = 2010 | ||
| | | pages = 110 | ||
}} | }} | ||
[[Category:Histology]] | [[Category:Histology]] | ||
[[Category:Embryology]] | [[Category:Embryology]] | ||
Revision as of 14:51, 3 January 2023
Acrosome reaction' (acrosomal reaction) is the release of enzymes from the acrosome that dissolve the zona pellucida and allow the sperm to fuse with the egg. The sperm must first undergo capacitation - the interaction of the sperm with the fallopian tubeu epithelium - when the glycocalyxu is removed from the acrosome sac.
Course of reaction
The zona pellucida (the glycoprotein envelope surrounding the ovule) contains zonal protein 3 (ZP3 ligand), which induces and controls the acrosome reaction. Release of enzymes from the acrosomal sac causes disruption of the intercellular junctions of the corona radiata and disruption of the zona pellucida. The spermatozoa thus come into contact with the egg membrane. This is followed by membrane fusion by interaction of integrin oolemma with the disintegrins of the sperm membrane.
Acrosome
Sperm organelle containing lytic enzymes for disrupting cell junctions. It is located at the apex of the sperm head. It is formed by the process of gametogenesis (spermiogenesis) by the union of several secretory vesicles from the Golgi complexs into one. The acrosome contains the following enzymes:
- protease- acrosin-protease (related to trypsin);
- glycosidase - hyaluronidase;
- lipase - phospholipase.
References
Related articles
Resources
- SADLER, Thomas, W – SINHA, M.D. Langman's Medical Embryology : Textbook for medical students and general nursing and midwifery students. 1st Czech edition. Grada, 2011. pp. 414. ISBN 978-80-247-2640-3.
- VAJNER, Luděk – UHLÍK, Jiří – KONRÁDOVÁ, Václava. Medical histology. 1, Cytology and general histology. 1. edition. Karolinum, 2010. pp. 110. ISBN 978-80-246-1860-9.
