Alveolo-Capillary Membrane: Difference between revisions
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For respiration to be effective, the '''diffusion path''' must be '''as short as possible'''. Therefore, sites that are functionally important (sites that do not contain second-order pneumocytes, no cell nuclei, interstitial ligament) have a thickness of '''0,6 μm'''<ref name "Lüllmann">{{Cite | For respiration to be effective, the '''diffusion path''' must be '''as short as possible'''. Therefore, sites that are functionally important (sites that do not contain second-order pneumocytes, no cell nuclei, interstitial ligament) have a thickness of '''0,6 μm'''<ref name "Lüllmann">{{Cite | ||
| | | type = book | ||
| isbn = 978-80-247-3729-4 | | isbn = 978-80-247-3729-4 | ||
| | | surname1 = Lüllmann-Rauch | ||
| | | name1 = Renate | ||
| | | title = Histologie | ||
| | | number = 1 | ||
| | | place = Praha | ||
| | | publisher = Grada | ||
| | | year = 2012 | ||
| | | pages = 576 | ||
}}</ref>. If we also measure the interalveolar septa, then the mean thickness is 2 μm. | }}</ref>. If we also measure the interalveolar septa, then the mean thickness is 2 μm. | ||
<noinclude> | <noinclude> | ||
=== | === References === | ||
* {{ | * {{Cite | ||
| | | type = book | ||
| isbn = 978-80-247-3729-4 | | isbn = 978-80-247-3729-4 | ||
| | | surname1 = Lüllmann-Rauch | ||
| | | name1 = Renate | ||
| | | title = Histologie | ||
| | | number = 1 | ||
| | | place = Praha | ||
| | | publisher = Grada | ||
| | | year = 2012 | ||
| | | pages = 576 | ||
}} | }} | ||
* {{ | * {{Cite | ||
| | | type = web | ||
| | | surname1 = Fontana | ||
| | | name1 = Josef | ||
| | | surname2 = Trnka | ||
| | | name2 = Jan | ||
| | | surname3 = Maďa | ||
| | | name3 = Patrik | ||
| | | others = ano | ||
| url = http://fblt.cz/ | | url = http://fblt.cz/ | ||
| | | title = Funkce buněk a lidského těla | ||
| | | subtitle = Multimediální skripta 3.LF | ||
| | | cited = 2015-12-09 | ||
}} | }} | ||
*{{ | *{{Cite | ||
| | | type = book | ||
| isbn = 978-80-246-0615-6 | | isbn = 978-80-246-0615-6 | ||
| | | surname1 = Nečas | ||
| | | name1 = Emanuel | ||
| | | surname2 = Šulc | ||
| | | name2 = Karel | ||
| | | surname3 = Vokurka | ||
| | | name3 = Martin | ||
| | | others = ano | ||
| | | title = Patologická fyziologie orgánových systémů. Část I | ||
| | | number = 1 | ||
| | | place = Praha | ||
| | | publisher = Karolinum | ||
| | | year = 2006 | ||
| | | pages = 377 | ||
}} | }} | ||
=== | ===References=== | ||
<references /> | <references /> | ||
</noinclude> | </noinclude> | ||
[[ | [[Category: Histology]] | ||
[[ | [[Category: Physiology]] | ||
[[ | [[Category: Pneumology]] | ||
Revision as of 21:11, 25 November 2020
This article has been translated from WikiSkripta; the translation needs to be checked.
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The exchange of respiratory gases takes place through the alveolo-capillary membrane (hemo-respiratory barrier). It is a thin layer (0.6–2 μm) that is part of the pulmonary alveoli. The total size of the alveolo-capillary membrane is 60–160 m2[1].
Layers alveolocapillary membranes
In the thinnest places, the membrane consists of the following 6 layers :
- A layer of fluid containing a surfactanton the inner surface of the alveoli
- Alveolar epithelium - bodies of first order pneumocytes
- Basal membrane of the epithelium
- Interstitium between the basement membrane of the epithelium and the endothelium (a very thin tissue space that contains collagen and elastin fibers)
- Basal membrane of the endothelium
- Capillary endothelium
For respiration to be effective, the diffusion path must be as short as possible. Therefore, sites that are functionally important (sites that do not contain second-order pneumocytes, no cell nuclei, interstitial ligament) have a thickness of 0,6 μm[2]. If we also measure the interalveolar septa, then the mean thickness is 2 μm.
References
- Incomplete citation of publication. LÜLLMANN-RAUCH, Renate. Histologie. Grada, 2012. pp. 576. ISBN 978-80-247-3729-4.
- Incomplete citation of web. FONTANA, Josef – TRNKA, Jan – MAĎA, Patrik. [cit. 2015-12-09]. <http://fblt.cz/>.
- Incomplete citation of publication. NEČAS, Emanuel – ŠULC, Karel – VOKURKA, Martin. Patologická fyziologie orgánových systémů. Část I. Karolinum, 2006. pp. 377. ISBN 978-80-246-0615-6.
