Diseases of the upper respiratory tract: Difference between revisions
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'''Onemocnění horních cest dýchacích''' (HCD) patří mezi nejčastější příčiny nemocnosti dětí ve všech věkových skupinách. Etiologie obvykle bývá zpočátku virová (u kojenců a batolat převažují ''adenoviry'', u dětí školního věku ''rhinoviry, coronaviry, virus influenzae A a B, parainfluenzae''). Na virem poškozenou sliznici následně snáze nasedá bakteriální infekce. Hlavními respiračními patogeny jsou ''[[Haemophilus influenzae]], [[Staphylococcus aureus]], [[Streptococcus pyogenes]], [[Moraxella catarrhalis]]''.
'''Upper respiratory tract disease''' is one of the most common causes of morbidity in children of all ages. The etiology is usually viral at first (''adenoviruses'' predominate in infants and toddlers, ''rhinoviruses'', ''coronaviruses'', ''influenzae A and B virus'', ''parainfluenzae'' in school-age children). Bacterial infections then become more easily attached to the virus-damaged mucosa. The main respiratory pathogens are ''[[Haemophilus influenzae]], Staphylococcus aureus, Streptococcus pyogenes, [[Moraxella catarrhalis]]''.
=== Akutní onemocnění HCD ===
=== Acute upper respiratory tract disease ===
* [[Akutní rinitida]] a rinofaryngitida;
* Acute rhinitis and rhinopharyngitis;
* [[akutní tonzilitida]] a tonzilofaryngitida;
* acute tonsillitis and tonsillopharyngitis;
* [[akutní sinusitida|akutní (rino)sinusitida]];
* acute (rhino)sinusitis;
* [[akutní mediootitida]];
* acute mediothitis;
* [[akutní epiglotitida]];
* acute epiglottitis;
* [[akutní subglotická laryngitida]].
* acute subglottic laryngitis.
=== Chronické onemocnění HCD ===
=== Chronic upper respiratory tract disease ===
* [[Chronická rinitida]] (alergická, infekční, nealergická neinfekční);
* Chronic rhinitis (allergic, infectious, non-allergic non-infectious);
* [[chronický zánět nosohltanu]];
* chronic nasopharyngitis;
* [[chronická faryngitida]];
* chronic pharyngitis;
* [[chronická tonzilitida]].
* chronic tonsillitis.
== Akutní subglotická laryngitida ==
== Acute subglottic laryngitis ==
Akutní subglotická laryngitida (ASL) představuje zánětlivý otok v subglotickém prostoru při akutní virové infekci, který může vést k náhle vzniklé sufokaci. Obstrukce HCD je způsobena zánětlivým otokem sliznice a podslizničního prostoru v oblasti hrtanu. Mezi etiologická agens patří ''parainfluenza, adenoviry, RSV''.
Acute subglottic laryngitis (ASL) is an inflammatory swelling in the subglottic space in an acute viral infection that can lead to sudden suffocation. Upper airway obstruction is caused by inflammatory swelling of the mucosa and submucosal space in the larynx. Etiological agents include ''parainfluenza'', adenoviruses, ''RSV''. The frequency is very common, especially in the winter months (November-April). Children from infancy to about 6 years of age are most often affected, but exceptions are the rule.
Frekvence je velmi častá, zejména v zimních měsících (listopad–duben). Nejčastěji jsou postiženy děti od kojeneckého věku do cca 6&thinsp;let, ale výjimky jsou pravidlem.<ref name="jh">HAVRÁNEK, Jiří: ''Infekce horních dýchacích cest'' [učební text]</ref>
== Acute epiglottitis ==
{{Podrobnosti|Akutní laryngitida}}
Acute epiglottitis is a phlegm of the laryngeal flap during invasive hemophilic infection, which can subsequently lead to sepsis. ''[[Haemophilus influenzae]] type b'' rarely other causative agents, is used etiologically. Children aged 2–7 are most often affected. The introduction of vaccination against ''Haemophilus influenzae type b'' into the routine calendar has practically eliminated the disease.
== Akutní epiglotitida ==
== Bacterial tracheitis ==
Akutní epiglotitida je phlegmona příklopky hrtanové při invazivní hemofilové infekci, kdy následně může dojít i k rozvoji sepse. Etiologicky se uplatňuje ''[[Haemophilus influenzae]] typ b'' opouzdřený, vzácně jiní vyvolavatelé. Nejčastěji bývají postiženy děti ve věku 2–7 let. Zavedení očkování proti ''Haemophilus influenzae typu b'' do rutinního kalendáře došlo prakticky k eliminaci onemocnění.<ref name="jh"/>
It is a purulent bacterial inflammation of the trachea with a tendency to form pablans, most often in children aged 6 months to 12 years. The most common cause are ''Staphylococcus aureus, [[Haemophilus influenzae]]'' and ''Streptococcus pneumoniae.'' Initially, patients present a picture of an upper respiratory tract infection lasting several hours to days. Gradually, '''inspiratory dyspnoea''' develops, but mostly with indistinct '''stridor''', the '''cough''' is barking to tracheal, the sore throat is constant, the voice is hoarse, but there is no dysphagia. At the same time, there is an onset of '''alteration in the general condition''' (clinical picture of "toxic", non-improving laryngitis).The auditory finding is poor, we can find bronchial phenomena. Due to severe upper airway obstruction and alterations in the general condition, we almost always approach intubation and artificial ventilation.
{{Podrobnosti|Akutní epiglotitida}}
=== Differential diagnostics ===
== Bakteriální tracheitida ==
Jedná se o hnisavý bakteriální zánět trachey s tendencí k tvorbě pablán, nejčastěji u dětí ve věku 6 měsíců až 12 let. Etiologicky se uplatňují ''[[Staphylococcus aureus]], [[Haemophilus influenzae]] a [[Streptococcus pneumoniae]]''.
Zpočátku se pacienti prezentují obrazem infekce horních dýchacích cest s trváním několika hodin až dní. Postupně se rozvíjí '''inspirační dyspnoe''', ale většinou s nevýrazným stridorem, '''kašel''' je '''štěkavý až tracheální''', bolest v krku nekonstantní, '''hlas''' je '''chraplavý''', ale dysfagie není. Současně dochází k nástupu '''alterace celkového stavu''' (klinicky obraz „toxické“, nelepšící se laryngitidy). Poslechový nález je chudý, můžeme nacházet bronchitické fenomény.
Vzhledem k těžké obstrukci horních dýchacích cest a alteraci celkového stavu přistupujeme skoro vždy k [[Intubace (pediatrie)|intubaci]] a UPV.<ref name="jh"/>
{{Podrobnosti|Bakteriální tracheitida}}
=== Diferenciální diagnostika ===
{| class="wikitable"
{| class="wikitable"
! onemocnění/příznaky !! [[Akutní laryngitida]] !! [[Bakteriální tracheitida]] !! [[Akutní epiglotitida]]<ref name="jh"/>
! diseases/symptoms !! Acute laryngitis !! Bacterial tracheitis !! Acute epiglottitis
|-
|-
!poloha dítěte
!child's position
| neovlivňuje dušení || neovlivňuje dušení || dítě se vleže dusí, brání se položení, chce sedět v předklonu
| does not affect suffocation || does not affect suffocation || the child suffocates while lying down, resists laying down, wants to sit in a forward bend
|-
|-
!charakter dýchání
!the nature of breathing
| usilovné, zatahuje měkké části hrudníku || inspirační dyspnoe, ale s většinou nevýrazným stridorem || opatrné, povrchní, dítě je na „dobré“ dýchání soustředěno
| hard, pulls the soft parts of the chest || inspiratory dyspnoea, but with mostly indistinct stridor || careful, superficial, the child is focused on breathing
|-
|-
!polykání
!swallowing
| dobré || zpravidla dobré || špatné, nepolyká ani sliny, které proto mohou vytékat z úst
| well || usually good || bad, does not swallow saliva, which can therefore flow out of the mouth
|-
|-
! tělesná teplota
! body temperature
| zpravidla subfebrilie|| febrilie || febrilie
| usually subfebrile|| febrile || febrile
|-
|-
!kašel
!cough
| suchý, laryngeální || suchý, laryngeální || není, dítě se pro bolest v krku „bojí“ kašlat
| dry, laryngeal || dry, laryngeal || there is no cough, the child is "afraid" to cough due to a sore throat
|-
|-
!stridor
!stridor
|inspirační || inspirační || bublavý, srkavý zvuk nahromaděného hlenu v inspiriu i exspiriu
|inspirational || inspirational || cough is a bubbling, sipping sound of accumulated mucus in inspiration and expiration
|-
|-
!výskyt
!occurrence
|sezonní výskyt || kdykoli během roku || kdykoli během roku
|seasonal occurrence || occurrence is at any time during the year || occurrence is at any time during the year
|-
|-
!začátek a průběh
!onset and course
| začátek náhlý, zpravidla v noci, zhoršení během desítek minut || postupný rozvoj dyspnoe || začátek kdykoli během 24 hodin, zhoršení během hodin
| sudden onset, usually at night, worsening within tens of minutes || gradual development of dyspnoea || start at any time within 24 hours, worsening within hours
|-
|-
!reakce na kortikosteroidy a [[adrenalin]]
!reactions to corticosteroids and adrenaline
|ústup příznaků během desítek minut || žádný účinek || žádný účinek
|relief of symptoms within tens of minutes || no effect || no effect
|-
|-
!bolest v krku
!sore throat
|není || obvykle není || výrazná
| - || sore throat usually does not occur || distinctive
|-
|-
!objektivní nález v krku
!objective finding in the throat
| katarální zánět, epiglotis štíhlá, málo sekretu || normální, ev. katarální nález || oteklá, rudá epiglotis a nahromaděný hlen – „jezírko“
| bluetongue, slender epiglottis, little secretion || normal, ev. bluetongue finding || swollen, red epiglottis and accumulated mucus
|-
|-
!věk
!age
|3 měsíce až 5 let || 6 měsíců až 12 let || 2 7 let
|3 months to 5 years || 6 months to 12 years || 2 to 7 years
|}
|}
== Retrofaryngeální absces/flegmona ==
Retropharyngeální absces (RA) je hluboká krční infekce, která se typicky vyskytuje u dětí. Dojde-li k dalšímu šíření infekce, může nastat ohrožení života. RA vzniká nejčastěji na podkladě abscedující lymphadenitidy, po předcházející infekci horních dýchacích cest, typicky v období mezi 2.–4. rokem života. RA svými příznaky velmi připomíná epiglotitidu.<ref name="jh"/>
{{Podrobnosti|Retrofaryngeální absces}}
== Peritonsilární absces ==
Iniciální symptomatologie peritonzilárního abscesu připomíná epiglotitidu. Nejčastější věkovou skupinou jsou ale '''starší školáci'''. Děti mívají '''horečku, zastřený hlas a mohou slinit'''. Charakteristickým příznakem může být i trismus. Při větší velikosti abscesu si děti stěžují na dušnost.


Při aspekci oropharyngu vidíme asymetrické zduření patrových oblouků, jednostrannou povlakovou anginu s akcentací bolesti. Diagnózu potvrdí lékař ORL. Při fluktuujícím abscesu je indikací chirugická incize a drenáž. V diferenciální diagnostice abscesu a cellulitidy můžeme recentně využít intraorální ultrazvukovou sondu.<ref name="jh"/>
== Retropharyngeal abscess / phlegmon ==
Retropharyngeal abscess (RA) is a deep throat infection that typically occurs in children. If the infection spreads further, it can be life-threatening. RA most often occurs on the basis of abscessed lymphadenitis, after a previous infection of the upper respiratory tract, typically in the period between 2-4. year of life. RA is very similar to epiglottitis with its symptoms.
== Peritonsillar abscess ==
The initial symptomatology of the peritonsillar abscess resembles epiglottitis. But the most common age group is '''older schoolchildren'''. Children tend to have a '''fever''', a '''muffled voice''' and may '''drool'''. Trismus can also be a characteristic symptom. With a larger abscess, children complain of shortness of breath.
 
In the aspect of the oropharynx, we see asymmetric swelling of the floor arches, unilateral coating angina with accentuation of pain. The diagnosis is confirmed by an ENT doctor. With a fluctuating abscess, a surgical incision and drainage are indicated. We can recently use an intraoral ultrasound probe in the differential diagnosis of abscess and cellulitis.

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Upper respiratory tract disease is one of the most common causes of morbidity in children of all ages. The etiology is usually viral at first (adenoviruses predominate in infants and toddlers, rhinoviruses, coronaviruses, influenzae A and B virus, parainfluenzae in school-age children). Bacterial infections then become more easily attached to the virus-damaged mucosa. The main respiratory pathogens are Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, Moraxella catarrhalis.

Acute upper respiratory tract disease

  • Acute rhinitis and rhinopharyngitis;
  • acute tonsillitis and tonsillopharyngitis;
  • acute (rhino)sinusitis;
  • acute mediothitis;
  • acute epiglottitis;
  • acute subglottic laryngitis.

Chronic upper respiratory tract disease

  • Chronic rhinitis (allergic, infectious, non-allergic non-infectious);
  • chronic nasopharyngitis;
  • chronic pharyngitis;
  • chronic tonsillitis.

Acute subglottic laryngitis

Acute subglottic laryngitis (ASL) is an inflammatory swelling in the subglottic space in an acute viral infection that can lead to sudden suffocation. Upper airway obstruction is caused by inflammatory swelling of the mucosa and submucosal space in the larynx. Etiological agents include parainfluenza, adenoviruses, RSV. The frequency is very common, especially in the winter months (November-April). Children from infancy to about 6 years of age are most often affected, but exceptions are the rule.

Acute epiglottitis

Acute epiglottitis is a phlegm of the laryngeal flap during invasive hemophilic infection, which can subsequently lead to sepsis. Haemophilus influenzae type b rarely other causative agents, is used etiologically. Children aged 2–7 are most often affected. The introduction of vaccination against Haemophilus influenzae type b into the routine calendar has practically eliminated the disease.

Bacterial tracheitis

It is a purulent bacterial inflammation of the trachea with a tendency to form pablans, most often in children aged 6 months to 12 years. The most common cause are Staphylococcus aureus, Haemophilus influenzae and Streptococcus pneumoniae. Initially, patients present a picture of an upper respiratory tract infection lasting several hours to days. Gradually, inspiratory dyspnoea develops, but mostly with indistinct stridor, the cough is barking to tracheal, the sore throat is constant, the voice is hoarse, but there is no dysphagia. At the same time, there is an onset of alteration in the general condition (clinical picture of "toxic", non-improving laryngitis).The auditory finding is poor, we can find bronchial phenomena. Due to severe upper airway obstruction and alterations in the general condition, we almost always approach intubation and artificial ventilation.

Differential diagnostics

diseases/symptoms Acute laryngitis Bacterial tracheitis Acute epiglottitis
child's position does not affect suffocation does not affect suffocation the child suffocates while lying down, resists laying down, wants to sit in a forward bend
the nature of breathing hard, pulls the soft parts of the chest inspiratory dyspnoea, but with mostly indistinct stridor careful, superficial, the child is focused on breathing
swallowing well usually good bad, does not swallow saliva, which can therefore flow out of the mouth
body temperature usually subfebrile febrile febrile
cough dry, laryngeal dry, laryngeal there is no cough, the child is "afraid" to cough due to a sore throat
stridor inspirational inspirational cough is a bubbling, sipping sound of accumulated mucus in inspiration and expiration
occurrence seasonal occurrence occurrence is at any time during the year occurrence is at any time during the year
onset and course sudden onset, usually at night, worsening within tens of minutes gradual development of dyspnoea start at any time within 24 hours, worsening within hours
reactions to corticosteroids and adrenaline relief of symptoms within tens of minutes no effect no effect
sore throat - sore throat usually does not occur distinctive
objective finding in the throat bluetongue, slender epiglottis, little secretion normal, ev. bluetongue finding swollen, red epiglottis and accumulated mucus
age 3 months to 5 years 6 months to 12 years 2 to 7 years

Retropharyngeal abscess / phlegmon

Retropharyngeal abscess (RA) is a deep throat infection that typically occurs in children. If the infection spreads further, it can be life-threatening. RA most often occurs on the basis of abscessed lymphadenitis, after a previous infection of the upper respiratory tract, typically in the period between 2-4. year of life. RA is very similar to epiglottitis with its symptoms.

Peritonsillar abscess

The initial symptomatology of the peritonsillar abscess resembles epiglottitis. But the most common age group is older schoolchildren. Children tend to have a fever, a muffled voice and may drool. Trismus can also be a characteristic symptom. With a larger abscess, children complain of shortness of breath.

In the aspect of the oropharynx, we see asymmetric swelling of the floor arches, unilateral coating angina with accentuation of pain. The diagnosis is confirmed by an ENT doctor. With a fluctuating abscess, a surgical incision and drainage are indicated. We can recently use an intraoral ultrasound probe in the differential diagnosis of abscess and cellulitis.