Chondroma: Difference between revisions
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'''Chondroma''' is a benign tumor formed by mature, lobularly arranged cartilaginous tissue, it occurs in the 2nd − 5th decade. Microscopically, it consists of well-differentiated tissue similar to hyaline [[cartilage]], nodularly arranged. We divide it into: | '''Chondroma''' is a benign tumor formed by mature, lobularly arranged cartilaginous tissue, it occurs in the 2nd − 5th decade. Microscopically, it consists of well-differentiated tissue similar to hyaline [[cartilage]], nodularly arranged. We divide it into: | ||
# '''enchondroma''' – grows inside the bone, most often phalanges of the hands and feet; | # '''enchondroma''' – grows inside the bone, most often phalanges of the hands and feet; | ||
Revision as of 18:46, 19 February 2022
Chondroma is a benign tumor formed by mature, lobularly arranged cartilaginous tissue, it occurs in the 2nd − 5th decade. Microscopically, it consists of well-differentiated tissue similar to hyaline cartilage, nodularly arranged. We divide it into:
- enchondroma – grows inside the bone, most often phalanges of the hands and feet;
- juxtacortical chondroma – grows on the surface of the bone.
The multiple occurrence of chondromas even in long bones is called Ollier's disease (risk of malignancy).
Zvláštním nádorem z chrupavčité tkáně je chondrohamartom. Vzniká typicky subpleurálně v plicích z odštěpených kmenových buněk nezapojených do okolní tkáně (hamarcie). Mikroskopicky jej tvoří dobře diferencovaná chrupavčitá tkáň s komůrkovými buňkami, na periferii je příměs dalších tkání (respirační epitel, hladká svalovina, tuková tkáň). Nádor je řazen mezi benigní, avšak s určitým rizikem malignizace.
A special tumor of cartilaginous tissue is chondrohamartoma. It typically originates subpleurally in the lungs from cleaved stem cells not involved in the surrounding tissue (hamarcia). Microscopically, it consists of well-differentiated cartilaginous tissue with compartment cells, at the periphery there is an admixture of other tissues (respiratory epithelium, smooth muscle, adipose tissue). The tumor is classified as benign, but with a certain risk of malignancy.
Ollier's disease - Multiple enchondromas in the proximal humerus
Enchondroma microscopic
Enchondroma - femur RTG
Enchondrom - femur MRI
References
Related Articles
Source
- PASTOR, Jan. Langenbeck's medical web page [online]. [cit. 201-04-18]. <http://langenbeck.webs.com>.
