Serum amyloid A: Difference between revisions
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*[[Acute phase reactants]] | |||
Revision as of 20:40, 4 April 2022
Serum amyloid A refers to a group of proteins belonging to the acute phase reactants. These are proteins of the apoprotein family. The functions of SAA are as follows:
- restriction of cholesterol transport to the liver,
- chemotaxis,
- induction of extracellular matrix degrading enzymes..
SAA is involved in the development of a number of pathologies:
- long-term elevated SAA levels are a risk factor for atherosclerosis,
- Long-term overproduction of SAA can lead to secondary amyloidosis.
