Glucose-alanine cycle: Difference between revisions
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[[File:The glucose-alanine cycle.jpg|thumb|The glucose-alanine cycle]] | |||
'''Alanine''', on the one hand, participates in the '''transfer of ammonia''' through the blood, and on the other hand, through pyruvate, serves as an important '''source of carbon''' for the process of [[gluconeogenesis]]. | '''Alanine''', on the one hand, participates in the '''transfer of ammonia''' through the blood, and on the other hand, through pyruvate, serves as an important '''source of carbon''' for the process of [[gluconeogenesis]]. | ||
Latest revision as of 18:55, 14 December 2022
Alanine, on the one hand, participates in the transfer of ammonia through the blood, and on the other hand, through pyruvate, serves as an important source of carbon for the process of gluconeogenesis.
See Glucose Breakdown and Synthesis for more detailed information.
The glucose-alanine cycle is an interorgan metabolic pathway occurring between muscle cells and the liver.
- After pyruvate is formed in muscle cells, it undergoes transamination to form alanine.
- It is released into the blood, which transports it to the liver, where it is converted back into pyruvate by transamination , which can be involved in the process of gluconeogenesis.
- The resulting glucose enters the muscles through the blood and the whole cycle is closed.
The transferred amino group (ammonia) goes to the urea cycle.
