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'''The International Classification of Diseases for Oncology''' (MKN-O, ''International Classification of Diseases for Oncology'' , ICD-O) is derived from the [[International classification of diseases|International Classification of Diseases]] for oncological diagnoses. The third revision of the ICD-O is currently in use. Tumors are coded in the following axes:
'''The International Classification of Diseases for Oncology''' (MKN-O, ''International Classification of Diseases for Oncology'' , ICD-O) is derived from the [[International classification of diseases|International Classification of Diseases]] for oncological diagnoses. The third revision of the ICD-O is currently in use. Tumors are coded in the following axes:
*topography
*topography
*morphology
*morphology
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'''The biological behavior code ( ''Y'' ) can take on the following values:'''
'''The biological behavior code ( ''Y'' ) can take on the following values:'''
*'''''0''''' – benign tumor
*'''''0''''' – benign tumor
*'''''1''''' –  uncertain behavior, it is not certain whether it is a benign or malignant tumor
*'''''1''''' –  uncertain behavior, it is not certain whether it is a benign or malignant tumor
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'''The differentiation code has the meaning of histological grading and differentiation:'''
'''The differentiation code has the meaning of histological grading and differentiation:'''
*'''''1''''' – well differentiated
*'''''2''''' – moderately well differentiated
*'''''3''''' – poorly differentiated
*'''''4''''' – undifferentiated, anaplastic
*'''''9''''' – differentiation not determined, not stated or cannot be used


'''In the case of [[Malignant lymphoma|lymphomas]] and [[Leukemia|leukemias]], instead of the differentiation code, the gross immunophenotype is given in the National Cancer Registry:'''


 
*'''''5''''' – immunoprofile corresponds to [[T lymphocytes]]
*'''''1''''' – dobře diferencovaný
*'''''6''''' – immunoprofile corresponds to [[B lymphocytes]]
*'''''2''''' – středně dobře diferencovaný
*'''''7''''' – immunoprofile of null cells (non-B non-T cells)
*'''''3''''' – špatně diferencovaný
*'''''8''''' – immunoprofile corresponds to [[NK cells]]
*'''''4''''' – nediferencovaný, anaplastický
*'''''9''''' – cell type unspecified, not specified or unusable
*'''''9''''' – diferenciace neurčena, neuvedena nebo nelze použít
 
'''V případě [[Lymfom|lymfomů]] a [[Leukémie|leukémií]] je místo kódu diferenciace v Národním onkologickém registru uváděn hrubý imunofenotyp:'''
 
*'''''5''''' – imunoprofil odpovídá [[T-lymfocyty|T lymfocytům]]
*'''''6''''' – imunoprofil odpovídá [[B-lymfocyty|B lymfocytům]]
*'''''7''''' – imunoprofil null buněk (non-B non-T buňky)
*'''''8''''' – imunoprofil odpovídá [[NK buňky|NK buňkám]]
*'''''9''''' – buněčný typ neurčen, neudán nebo nepoužitelný





Revision as of 10:34, 30 March 2023


The International Classification of Diseases for Oncology (MKN-O, International Classification of Diseases for Oncology , ICD-O) is derived from the International Classification of Diseases for oncological diagnoses. The third revision of the ICD-O is currently in use. Tumors are coded in the following axes:

  • topography
  • morphology
  • biological behaviour
  • differentiation

The classification is expressed by a combination of a three- to four-digit alphanumeric code of topography (e.g. C01.1) b a five-digit code XXXX/Y, where the first four digits indicate the morphological type of the tumor and the digit after the slash biological behavior. The next (optional) number (sometimes listed second after the slash in data collections) indicates the degree of differentiation of the tumor. Morphological codes ( XXXX ) are always four-digit numbers from the interval 8000 to 9989.

The biological behavior code ( Y ) can take on the following values:

  • 0 – benign tumor
  • 1 – uncertain behavior, it is not certain whether it is a benign or malignant tumor
  • 2 – tumor in situ, non-invasive
  • 3 – malignant tumor, primary
  • 6 – malignant tumor, metastatic (not used in oncology registries)
  • 9 – malignant tumor, origin cannot be determined (not used in oncology registries)

The differentiation code has the meaning of histological grading and differentiation:

  • 1 – well differentiated
  • 2 – moderately well differentiated
  • 3 – poorly differentiated
  • 4 – undifferentiated, anaplastic
  • 9 – differentiation not determined, not stated or cannot be used

In the case of lymphomas and leukemias, instead of the differentiation code, the gross immunophenotype is given in the National Cancer Registry:

  • 5 – immunoprofile corresponds to T lymphocytes
  • 6 – immunoprofile corresponds to B lymphocytes
  • 7 – immunoprofile of null cells (non-B non-T cells)
  • 8 – immunoprofile corresponds to NK cells
  • 9 – cell type unspecified, not specified or unusable


Klasifikace je odvozena od klasifikace MKN-10. Kódování topografie/lokalizace tedy u zhoubných novotvarů většinou odpovídá MKN-10 kódu. Výjimku tvoří například kódy, které již v MKN-10 zohledňují morfologický typ novotvaru. Například kód C43.5 Zhoubný melanom trupu se v MKN-O kóduje C44.3 (Kůže trupu) 8720/3 (Maligní melanom NS).

Příklad interpretace kódování C24.1 M-8160/32:

  • C24 – (zhoubný) novotvar jiných a neurčených částí žlučových cest
  • C24.1 – nádor Vaterské papily
  • C24.1 8160 – cholangiokarcinom Vaterské papily
  • C24.1 8160/3 – (maligní) cholangiokarcinom Vaterské papily
  • C24.1 8160/32 – středně dobře diferencovaný cholangiokarcinom Vaterské papily

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Kategorie:Onkologie Kategorie:Patologie Kategorie:Zdravotnická statistika