Structure and function of individual parts of immunoglobulins. Classes of immunoglobulins, properties and functions. Monoclonal antibodies - preparation, use.: Difference between revisions
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(Created page with "Immunoglobulins are class of proteins produced by B cells and plasma cells. They serve as line of defense against pathogens that invade our body. <ref>''NCI Dictionary of Cancer terms'' (no date) ''Comprehensive Cancer Information - NCI''. Available at: <nowiki>https://www.cancer.gov/publications/dictionaries/cancer-terms/def/immunoglobulin</nowiki> (Accessed: 03 April 2025). </ref> The components of Immunoglobulins are two small polypeptide chains and two large polype...")
 
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Immunoglobulins are class of proteins produced by B cells and plasma cells. They serve as line of defense against pathogens that invade our body. <ref>''NCI Dictionary of Cancer terms'' (no date) ''Comprehensive Cancer Information - NCI''. Available at: <nowiki>https://www.cancer.gov/publications/dictionaries/cancer-terms/def/immunoglobulin</nowiki> (Accessed: 03 April 2025). </ref>  
Immunoglobulins are class of proteins produced by B cells and plasma cells. Another term used to refer to Immunoglobulins are antibodies. They serve as line of defense against pathogens that invade our body. <ref>''NCI Dictionary of Cancer terms'' (no date) ''Comprehensive Cancer Information - NCI''. Available at: <nowiki>https://www.cancer.gov/publications/dictionaries/cancer-terms/def/immunoglobulin</nowiki> (Accessed: 03 April 2025). </ref>  


The components of Immunoglobulins are two small polypeptide chains and two large polypeptide chains and in each respective pair, the polypeptide chains are identical. There are five major classes of immunoglobulins, of which the most abundant in human sera are gamma globulins. <ref>Lieberman, M. and Peet, A. (2018) ''Marks’ basic medical biochemistry: A clinical approach''. 5th edition. Philadelphia: Wolters Kluwer. </ref>
 
Antibodies as a monomer can be visualized as Y shaped The components of Immunoglobulins are two small polypeptide chains and two large polypeptide chains and in each respective pair, the polypeptide chains are identical. There are five major classes of immunoglobulins, of which the most abundant in human sera are gamma globulins. <ref>Lieberman, M. and Peet, A. (2018) ''Marks’ basic medical biochemistry: A clinical approach''. 5th edition. Philadelphia: Wolters Kluwer. </ref>


== Structure and function of Immunoglobulins ==
== Structure and function of Immunoglobulins ==
Key structures integral to the function of immunoglobulins  
Key structures integral to the function of immunoglobulins  
Variable regions and constant regions are found on both 


* Variable region  
* Variable region  

Revision as of 18:57, 3 April 2025

Immunoglobulins are class of proteins produced by B cells and plasma cells. Another term used to refer to Immunoglobulins are antibodies. They serve as line of defense against pathogens that invade our body. [1]


Antibodies as a monomer can be visualized as Y shaped The components of Immunoglobulins are two small polypeptide chains and two large polypeptide chains and in each respective pair, the polypeptide chains are identical. There are five major classes of immunoglobulins, of which the most abundant in human sera are gamma globulins. [2]

Structure and function of Immunoglobulins

Key structures integral to the function of immunoglobulins

Variable regions and constant regions are found on both

  • Variable region

References

  1. NCI Dictionary of Cancer terms (no date) Comprehensive Cancer Information - NCI. Available at: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/immunoglobulin (Accessed: 03 April 2025).
  2. Lieberman, M. and Peet, A. (2018) Marks’ basic medical biochemistry: A clinical approach. 5th edition. Philadelphia: Wolters Kluwer.