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- 15:36, 13 December 2024 Cateducated talk contribs created page Metabolism of pyrimidine nucleotides, regulation, inhibitors, disorders (Created page with "- Unlike the synthesis of the purine ring, which is synthesized on a pre-existing ribose-5-phosphate, the pyrimidine ring is synthesized before it is attached to the ribose-5-phosphate, which supplies the phosphoribosyl pyrophosphate (PRPP). - The source for pyrimidine ring atoms is glutamine, CO2 and aspartic acid. - In humans, the key step in the synthesis of pyrimidines is the synthesis of carbamoyl phosphate from glutamine and CO2, which is catalyzed by carmoyl p...")
