Tumors of peripheral nerves

Schwannoma on MRI

Peripheral nerve tumors can arise from Schwann cells, fibroblasts or perineural cells. Among the most important representatives are ``neurinoma (schwannoma, neurilema), ``neurofibroma, tumor of granular cells, as well as perineurioma, neurothecoma or malignant peripheral nerve sheath tumor (MPNST - malignant peripheral nerve sheath tumor).

Schwannoma

• Occurs either sporadically or as part of neurofibromatosis type II.

• In neurofibromatosis, these are usually multiple, chain-like tumors of various sizes on many nerves.

• The tumor usually destroys the fascicle from which it originates, the other fascicles follow the tumor and are stretched and compressed.
• They are also of considerable size.
• Therapy: the tumor has a capsule, the functional fascicles are usually easily separated from the capsule and only the tumor is removed.

• Paresis may improve over time.

• In the histological image, two variants of the tumor are visible, referred to as Antoni variant A and B. Type A is characterized by its staggered nuclei, such an arrangement is referred to as Verocay bodies. Type B shows a more myxoid character, it does not contain stapling of the nuclei. Both variants can be found in the same tumor.

Links

Related Articles

• Cubital Tunnel Syndrome
• Canalis carpi syndrome
• Meralgia paraesthetica

Source

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References

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  Incomplete publication citation. ZEMAN, Miroslav, et al. Special Surgery. Prague : Galen, 2004. 575 s. 978-80-7262-438-6.

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  Incomplete article citation.  ZEMAN, Miroslav, et al. 2004, year 2004, 

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  Incomplete database citation. Galen, ©2004. 

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  ZEMAN, Miroslav, et al. Special Surgery. Prague : Galen, 2004. 575 s. 978-80-7262-438-6} }

• {{#switch: book

|book =

  Incomplete publication citation. PROMOTED, Ctibor, et al. General pathology. Prague : Galen, 2011. 290 s. 978-80-7262-438-6.

|collection =

  Incomplete citation of contribution in proceedings. PROMOTED, Ctibor, et al. General pathology. Prague : Galen, 2011. 290 s. {{
  #if: 978-80-7262-773-8 |978-80-7262-438-6} }
  |article = 
  Incomplete article citation.  PROMOTED, Ctibor, et al. 2011, year 2011, 

|web =

  Incomplete site citation. PROMOTED, Ctibor, et al. Galen, ©2011. 

|cd =

  Incomplete carrier citation. PROMOTED, Ctibor, et al. Galen, ©2011. 

|db =

  Incomplete database citation. Galen, ©2011. 

|corporate_literature =

  PROMOTED, Ctibor, et al. General pathology. Prague : Galen, 2011. 290 s. 978-80-7262-438-6} }