Schilling's test

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Its positivity confirms a resorption disorder of vitamin B₁₂, (Addison-Bierner disease), when the level of this vitamin in the blood is typically reduced.

Procedure: Vitamín B₁₂ administered to them saturates the receptors in the tissues, then radionuclide-labeled vit.B₁₂ p.m.

• If absorption is intact, the radioactive vitamin is absorbed and excreted in the urine.
• In the case of malabsorption the vitamin leaves the body with the stool and less than 10% of the administered substance enters the urine.

Links

References

• STOŽICKÝ, František – PIZINGEROVÁ, Kateřina. Základy dětského lékařství. 1. edition. Praha : Karolinum, 2006. Chapter 359. pp. 257-258. ISBN 80-246-1067-1.