Disorders of myelination/Repetitorium

Concepts: Formation and function of the myelin sheath

Demyelinating and dysmyelinating disorders

• Slowing of AP propagation - desynchronization of conduction
• Incomplete nerve fiber isolation - AP propagation with decrement - AP skipping
• Limitation of mechanical protection

Central and peripheral demyelination

Major causes

• Sclerosis multiplex
• Diabetes mellitus

References

Related articles

• Multiple Sclerosis
• Chronic complications of diabetes

Source

• VÍZEK, Martin. Repetitorium [online]. [cit. 2012-01-17]. <https://web.archive.org/web/20130512032641/http://pf.lf2.cuni.cz/vyuka/repetitorium.html>.