Vitamin B1

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Vitamin B1 - structure

Dry beri beri

Beri beri wet

Thiamine ( vitamin B₁ ) is a coenzyme decarboxylase important for the metabolism of glucose and energy supply to nerve and muscle cells.

Source

Meat, fish, cereals, yeast, legumes.

Daily recommended intake for adults: 1-1.4 mg

Deficiency

The disease beri-beri

from a lack of dietary vitamin B₁ is found today in very poor population groups (e.g. refugees) in countries where people live mostly on polished/white rice. It may also develop in people who live mostly on refined wheat flour products and among alcoholics and food faddists.

A typical image consists of nervous disorders, especially peripheral nerves (dry beri beri), edema and heart disease (beri beri wet). Impaired absorption of vitamin B₁ occurs in alcoholics and is manifested by Wernicke encephalopathy.

Suboptimal thiamine status based on biochemical criteria in Europe was detected only in 4-6% of the population. Risk group are alcoholics.

Laboratory evaluation: thiamine excretion in the urine. In the absence of erythrocytes is reduced transketolase concentration in the blood and the sea is high concentrations of glycoxalate.

Excess

Signs of excess are not encountered.

Links

Related articles

• Fat Soluble Vitamins
• Water Soluble Vitamins

Bibliography

• BENCKO, Vladimir, et al. Hygiene and epidemiology : selected chapters. 2. edition. Prague. 2008. ISBN 80-246-0793-X.