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Uncontrolled ''tonic'' or ''clonic'' muscle spasms are referred to as convulsions , which, unlike fibrillation (muscle contraction without locomotion effect) or fasciculation (contraction of one muscle fiber), make any voluntary activity almost impossible. Although they can represent a completely benign phenomenon (typically a spasm on the dorsal side of the thigh during sports or while kneeling), they are often an accompanying phenomenon of serious diseases (encephalitis, epilepsy, intoxication, hypoglycemia). Whole-body convulsions are usually associated with a profound disturbance of consciousness.
Uncontrolled ''tonic'' or ''clonic'' muscle convulsions are referred to as convulsions , which, unlike fibrillation (muscle contraction without locomotion effect) or fasciculation (contraction of one muscle fiber), make any voluntary activity almost impossible. Although they can represent a completely benign phenomenon (typically a convulsion on the dorsal side of the thigh during sports or while kneeling), they are often an accompanying phenomenon of serious diseases (encephalitis, epilepsy, intoxication, hypoglycemia). Whole-body convulsions are usually associated with a profound disturbance of consciousness.


==Division according to the clinical picture==
==Division according to the clinical picture==
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*Metabolic (hypoglycemia)
*Metabolic (hypoglycemia)
*Neurological (typicky [[epilepsie]])
*Neurological (typically epilepsy)
*Expansive intracranial processes
*Expansive intracranial processes
*Febrile (febrile spasms occur mainly in children under 2-3 years old)
*Febrile (febrile spasms occur mainly in children under 2-3 years old)
*Affective respiratory seizures (in young children as a result of intense emotions - crying, laughing, when spasms are provoked by temporary apnea)
*Affective respiratory seizures (in young children as a result of intense emotions - crying, laughing, when convulsions are provoked by temporary apnea)
*Syncope (in this case it is rather rare - so-called convulsive syncope with short lasting spasms)
*Syncope (in this case it is rather rare - so-called convulsive syncope with short lasting spasms)
*Deficiency of vitamins or minerals (sodium, potassium, magnesium)or their excess
*Deficiency of vitamins or minerals (sodium, potassium, magnesium)or their excess
Line 22: Line 22:
*Endocrinopathy (hyperthyroidism)
*Endocrinopathy (hyperthyroidism)
*Eclampsia
*Eclampsia
*Intoxication  – typicky centrální psychostimulancia (deriváty [[amfetamin|budivých aminů]])
*Intoxication  – typically central psychostimulants (exciting amine derivates)
*Withdrawal syndrome ([[Delirium tremens]], withdrawal state after benzodiazepines or barbiturates)
*Withdrawal syndrome ([[Delirium tremens]], withdrawal state after benzodiazepines or barbiturates)
*Psychiatric
*Psychiatric
**v samotném důsledku psychiatrických onemocnění bez primárních neurologických příčin
**as a result of psychiatric diseases without primary neurological causes
**při neurodegenaritivních onemocněních
**in neurodegenerative diseases
**somatoformní (psychosomatické) poruchy - ''pseudokřeče''
**somatoform (psychosomatic) disorders - pseudospasms
**iantrogenně navozené prolongované velké záchvaty (GTCS) při [[Elektrokonvulzivní terapie|elektrokonvulziní terapii]] (case studies)
**iatrogenically induced prolonged grand mal seizures (GTCS) during electroconvulsive therapy (case studies)


==Treatment==
==Treatment==
It is always necessary to remember that spasms are a symptom, and it is therefore necessary to treat their cause, not the spasms themselves. However, the truth is that mainly clonic spasms can cause complications during treatment (during additional examinations, cannula insertion, etc.). In justified cases, it is therefore appropriate to suppress muscle contractions. IV benzodiazepines (e.g. diazepam) are typically used for this purpose, especially in the case of status epilepticus. Maybe there are other spasmolytics and myorelaxants . It is necessary to proceed with caution in case of intoxication with CNS depressants (alcohol, benzodiazepines, opiates), or in withdrawal states after benzodiazepines - in this case, e.g. Clomethiazole (Heminevrin) may be indicated.<br />
It is always necessary to remember that convulsions are a symptom, and it is therefore necessary to treat their cause, not the convulsions themselves. However, the truth is that mainly clonic convulsions can cause complications during treatment (during additional examinations, cannula insertion, etc.). In justified cases, it is therefore appropriate to suppress muscle contractions. IV benzodiazepines (e.g. diazepam) are typically used for this purpose, especially in the case of status epilepticus. Maybe there are other spasmolytics and myorelaxants. It is necessary to proceed with caution in case of intoxication with CNS depressants (alcohol, benzodiazepines, opiates), or in withdrawal states after benzodiazepines - in this case, e.g. Clomethiazole (Heminevrin) may be indicated.<br />


===Adult patients===
===Adult patients===
U většiny dospělých pacientů je příčinou křečového stavu '''[[Epilepsie|epileptický záchvat typu grand mal]]''', který obvykle dotyčného sám o sobě na životě neohrožuje. V takovém případě lze podat '''[[Benzodiazepiny|diazepam]]''' či '''[[Antiepileptika|fenytoin]]''' i.v. '''Diazepam''' podáváme i při '''křečích nejasného původu.'''
In most adult patients, the cause of the convulsive condition is a [[Epileptic seizure|grand mal epileptic seizure]] , which is usually not life-threatening in itself. In such a case, [[diazepam]] or [[phenytoin]] can be administered, and we also administer '''diazepam for convulsions of unclear origin'''.


Při podezření na '''[[hypoglykémie|hypoglykémii]]''' podáváme 0,2–0,5 g '''glukózy'''/kg i.v.
If [[hypoglycemia]] is suspected, we administer 0.2–0.5 g of '''glucose''' /kg IV


Pokud se jedná o '''tetanické křeče''', podáváme 10 ml 10% roztoku '''kalcium chloratum''' i.v., event. i 10 mg 10% roztoku '''magnesium sulfátu'''.
If it is '''tetanic convulsions''' , we administer 10 ml of a 10% solution of '''calcium chloratum''' iv, possibly. and 10 mg of a 10% solution of '''magnesium sulfate'''.


===Children===
===Children===
'''U dětí''' se jedná obvykle o '''febrilní křeče''', které lze zmírnit '''diazepamem''' podaným rektálně (i.v. aplikace může již tak dost traumatizované dítě ještě více rozrušit). Samozřejmostí jsou '''[[antipyretika]]'''. <br />Při podezření na '''tetanické křeče''' podáváme 5 ml 10% roztoku '''kalcium chloratum''' i. v + 5 ml 10% roztoku '''magnesium sulfátu'''
'''In children''', these are usually '''febrile convulsions''', which can be alleviated with '''diazepam''' administered rectally (even the application can make an already traumatized child even more agitated). [[Antipyretic|Antipyretics]] are a matter of course .  


Je důležité mít na paměti, že i samotné křeče mohou někdy pacienta ohrozit přímo na životě (aspirace regurgitovaného žaludečního obsahu, křečemi podmíněné pády spojené s úrazy hlavy).<br />
If '''tetanic convulsions''' are suspected, administer 5 ml of a 10% solution of '''calcium chloratum''' IV + 5 ml of a 10% solution of '''magnesium sulfate.'''


{{Cave|Křeče topické a křeče ''hemi'' — charakteru u dětí do půl roku a nad 6 let patří mezi urgentní stavy, zejména u pacientů s pozitivní rodinnou anamnézou}}{{Cave|}}
It is important to keep in mind that the convulsions themselves can sometimes directly endanger the patient's life (aspiration of regurgitated stomach contents, convulsion-induced falls associated with head injuries).<br />


==Odkazy==
{{Cave|Křeče topické a křeče ''hemi'' — charakteru u dětí do půl roku a nad 6 let patří mezi urgentní stavy, zejména u pacientů s pozitivní rodinnou anamnézou}}Topical convulsions and convulsions of a ''hemi'' -character in children under six months and over 6 years of age are urgent conditions, especially in patients with a positive family history{{Cave|}}
===Související články===


*[[Epilepsie]]
==Links==
*[[Intoxikace]]
===Related articles===
*[[Encefalitida]]
*[[Hypoglykémie]]
*[[Spazmolytika]]
*[[Myorelaxancia]]
*[[Parasympatolytika]]


===Použitá literatura===
*[[Epilepsy]]
*[[Intoxication]]
*[[Encephalitis]]
*[[Hypoglycemia]]
*[[Antispasmodics]]
*[[Muscle relaxant]]
*[[Parasympatholytics]]


* {{Citace
===References===
| typ = kniha
| isbn = 978-80-7262-707-3
| příjmení1 = Ambler
| jméno1 = Zdeněk
| titul = Základy neurologie
| podnázev = &nbsp;[učebnice pro lékařské fakulty]
| vydání = 7
| místo = Praha
| vydavatel = Galén
| rok = 2011
}}


* {{Citace
* AMBLER, Zdenek. ''Basics of neurology : [textbook for medical schools]. ''7th edition. Prague: Galén, 2011.  ISBN 978-80-7262-707-3
| typ = kniha
| isbn = 80-7262-214-5
| příjmení1 = Pokorný
| jméno1 = Jiří
| titul = Lékařská první pomoc
| vydání = 1
| místo = Praha
| vydavatel = Galén
| rok = 2005
| strany = 58-59, 205-209
}}


[[Kategorie:Anesteziologie]]
* HUMBLE, Jiří. ''Medical first aid. ''1st edition. Prague: Galén, 2005. pp. 58-59, 205-209. ISBN 80-7262-214-5
[[Kategorie:Endokrinologie]]
[[Kategorie:Interní propedeutika]]
[[Kategorie:Neodkladná medicína]]
[[Kategorie:Neurologie]]
[[Kategorie:Fyziologie]]

Revision as of 23:59, 30 December 2022

Uncontrolled tonic or clonic muscle convulsions are referred to as convulsions , which, unlike fibrillation (muscle contraction without locomotion effect) or fasciculation (contraction of one muscle fiber), make any voluntary activity almost impossible. Although they can represent a completely benign phenomenon (typically a convulsion on the dorsal side of the thigh during sports or while kneeling), they are often an accompanying phenomenon of serious diseases (encephalitis, epilepsy, intoxication, hypoglycemia). Whole-body convulsions are usually associated with a profound disturbance of consciousness.

Division according to the clinical picture

For clinical purposes, convulsions are most often divided into:

  • Clonic (Short-lived, repetitive twitches)
  • Tonic (muscle contractions lasting longer)
  • Tonic-clonic (combination of the two previous ones, typical of epileptic seizures of the grand mal type)

Division by cause

A simple aid for use over the patient - A dozen causes of unconsciousness

  • Metabolic (hypoglycemia)
  • Neurological (typically epilepsy)
  • Expansive intracranial processes
  • Febrile (febrile spasms occur mainly in children under 2-3 years old)
  • Affective respiratory seizures (in young children as a result of intense emotions - crying, laughing, when convulsions are provoked by temporary apnea)
  • Syncope (in this case it is rather rare - so-called convulsive syncope with short lasting spasms)
  • Deficiency of vitamins or minerals (sodium, potassium, magnesium)or their excess
  • Tetanic spasms
  • Endocrinopathy (hyperthyroidism)
  • Eclampsia
  • Intoxication – typically central psychostimulants (exciting amine derivates)
  • Withdrawal syndrome (Delirium tremens, withdrawal state after benzodiazepines or barbiturates)
  • Psychiatric
    • as a result of psychiatric diseases without primary neurological causes
    • in neurodegenerative diseases
    • somatoform (psychosomatic) disorders - pseudospasms
    • iatrogenically induced prolonged grand mal seizures (GTCS) during electroconvulsive therapy (case studies)

Treatment

It is always necessary to remember that convulsions are a symptom, and it is therefore necessary to treat their cause, not the convulsions themselves. However, the truth is that mainly clonic convulsions can cause complications during treatment (during additional examinations, cannula insertion, etc.). In justified cases, it is therefore appropriate to suppress muscle contractions. IV benzodiazepines (e.g. diazepam) are typically used for this purpose, especially in the case of status epilepticus. Maybe there are other spasmolytics and myorelaxants. It is necessary to proceed with caution in case of intoxication with CNS depressants (alcohol, benzodiazepines, opiates), or in withdrawal states after benzodiazepines - in this case, e.g. Clomethiazole (Heminevrin) may be indicated.

Adult patients

In most adult patients, the cause of the convulsive condition is a grand mal epileptic seizure , which is usually not life-threatening in itself. In such a case, diazepam or phenytoin can be administered, and we also administer diazepam for convulsions of unclear origin.

If hypoglycemia is suspected, we administer 0.2–0.5 g of glucose /kg IV

If it is tetanic convulsions , we administer 10 ml of a 10% solution of calcium chloratum iv, possibly. and 10 mg of a 10% solution of magnesium sulfate.

Children

In children, these are usually febrile convulsions, which can be alleviated with diazepam administered rectally (even the application can make an already traumatized child even more agitated). Antipyretics are a matter of course .

If tetanic convulsions are suspected, administer 5 ml of a 10% solution of calcium chloratum IV + 5 ml of a 10% solution of magnesium sulfate.

It is important to keep in mind that the convulsions themselves can sometimes directly endanger the patient's life (aspiration of regurgitated stomach contents, convulsion-induced falls associated with head injuries).

Cave!!!.pngTopical convulsions and convulsions of a hemi -character in children under six months and over 6 years of age are urgent conditions, especially in patients with a positive family historyCave!!!.png

Links

Related articles

References

  • AMBLER, Zdenek. Basics of neurology : [textbook for medical schools]. 7th edition. Prague: Galén, 2011.  ISBN 978-80-7262-707-3
  • HUMBLE, Jiří. Medical first aid. 1st edition. Prague: Galén, 2005. pp. 58-59, 205-209. ISBN 80-7262-214-5