Acetyl-CoA: Difference between revisions
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Acetyl coenzyme A is produced during the '''decarbocylation of pyruvate''' by the irreversible PDH reaction, a large amount is produced during the '''[[Beta-oxidation|β-oxidation]]''' of fatty acids, it is also produced during the '''degradation of some amino acids'''. It can be formed by the direct enzymatic connection of acetyl and coenzyme A with the consumption of [[Adenosine triphosphate|ATP]]. | Acetyl coenzyme A is produced during the '''decarbocylation of pyruvate''' by the irreversible PDH reaction, a large amount is produced during the '''[[Beta-oxidation|β-oxidation]]''' of fatty acids, it is also produced during the '''degradation of some amino acids'''. It can be formed by the direct enzymatic connection of acetyl and coenzyme A with the consumption of [[Adenosine triphosphate|ATP]]. | ||
It is a [[Macroergic compounds|macrogenic compund]], the macroergic bond energy is 32 kJ/mol.<ref | It is a [[Macroergic compounds|macrogenic compund]], the macroergic bond energy is 32 kJ/mol.<ref>DUŠKA, František and Jan TRNKA. ''Biochemistry in context Part I - basics of energy metabolism. ''1st edition. Prague: Karolinum, 2006. p. 25. <nowiki>ISBN 80-246-1116-3</nowiki> .</ref> | ||
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== Links == | == Links == | ||
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* [[Glycolysis]] | * [[Glycolysis]] | ||
=== References === | === References === | ||
* | * Wikipedia editors. ''Acetyl coenzyme A'' [online]. Wikipedia: The Open Encyclopedia, Last revised 5/6/2011, [cit. 2011-08-01]. < <nowiki>https://cs.wikipedia.org/wiki/Acetylcoenzym_A</nowiki> >. | ||
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=== External links === | === External links === | ||
* [[wikipedia:cs:Acetylkoenzym A|Acetyl coenzyme A]] | * [[wikipedia:cs:Acetylkoenzym A|Acetyl coenzyme A]] | ||
[[Category:Biochemistry]] | |||
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Latest revision as of 19:52, 16 January 2024
Acetyl coenzyme A (Ac-CoA) is a central molecule especially in the metabolism of carbohydrates, lipids, proteins and other substances. It is activated acetic acid to which coenzyme A is attached via a sulfur atom. In its excess, when the capacity of the citrate cycle is exceeded, it is a substrate for ketogenesis.
Acetyl coenzyme A is produced during the decarbocylation of pyruvate by the irreversible PDH reaction, a large amount is produced during the β-oxidation of fatty acids, it is also produced during the degradation of some amino acids. It can be formed by the direct enzymatic connection of acetyl and coenzyme A with the consumption of ATP.
It is a macrogenic compund, the macroergic bond energy is 32 kJ/mol.[1]
Links[edit | edit source]
Related articles[edit | edit source]
References[edit | edit source]
- Wikipedia editors. Acetyl coenzyme A [online]. Wikipedia: The Open Encyclopedia, Last revised 5/6/2011, [cit. 2011-08-01]. < https://cs.wikipedia.org/wiki/Acetylcoenzym_A >.
- ↑ DUŠKA, František and Jan TRNKA. Biochemistry in context Part I - basics of energy metabolism. 1st edition. Prague: Karolinum, 2006. p. 25. ISBN 80-246-1116-3 .
