Gastrinoma: Difference between revisions
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<noinclude></noinclude>[[File:ZES endo.jpg|thumb|Endoscopic picture of multiple peptic ulcers in the distal duodenum in a patient with Zollinger-Ellison syndrome based on gastrinoma.]] | <noinclude></noinclude>[[File:ZES endo.jpg|thumb|Endoscopic picture of multiple peptic ulcers in the distal duodenum in a patient with Zollinger-Ellison syndrome based on gastrinoma.]] | ||
'''Gastrinoma''' is a tumor with increased gastrin production, most often located in the pancreas. It is based on the G-cells of the pancreatic islets of Langerhans. Gastrinoma grows slowly but may be locally invasive; but more often it metastasizes. Due to increased gastrin production, high secretion of gastric juice with a high content of HCl and proteinases occurs, which leads to the repeated formation of peptic ulcers, especially in the duodenum, but they can also occur in the stomach, esophagus or jejunum. In 50% of cases, the patient develops diarrhea. The disease caused by excess of gastrin is called '''Zollinger-Ellison syndrome'''. | '''Gastrinoma''' is [[Tumor Markers|a tumor]] with increased [[gastrin]] production, most often located in the [[pancreas]]. It is based on the G-cells of the pancreatic islets of Langerhans. Gastrinoma grows slowly but may be locally invasive; but more often it [[Metastasis|metastasizes]]. Due to increased gastrin production, high secretion of [[gastric juice]] with a high content of HCl and proteinases occurs, which leads to the repeated formation of [[peptic ulcers]], especially in the duodenum, but they can also occur in the stomach, esophagus or jejunum. In 50% of cases, the patient develops [[Diarrheal diseases (signpost)|diarrhea]]. The disease caused by excess of gastrin is called '''[[Zollinger-Ellison syndrome]]'''. | ||
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== Links == | == Links == | ||
=== Related articles === | === Related articles === | ||
* [[ | * [[Pancreatic Cancer|Pancreatic tumors]] | ||
* [[ | * [[Zollinger-Ellison syndrome]] | ||
=== References === | === References === | ||
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* POVÝŠIL, Ctibor a Ivo ŠTEINER. ''Special pathology. ''2. edition. Prague : Galén : Karolinum, 2007. <nowiki>ISBN 978-80-246-1442-7</nowiki>. | * POVÝŠIL, Ctibor a Ivo ŠTEINER. ''Special pathology. ''2. edition. Prague : Galén : Karolinum, 2007. <nowiki>ISBN 978-80-246-1442-7</nowiki>. | ||
</noinclude> | </noinclude> | ||
[[Category:Oncology]] | |||
[[ | [[Category:Pathology]] | ||
[[ | [[Category:Gastroenterology]] | ||
[[ | [[Category:Internal medicine]] | ||
[[ | |||
Latest revision as of 17:13, 15 February 2022
Gastrinoma is a tumor with increased gastrin production, most often located in the pancreas. It is based on the G-cells of the pancreatic islets of Langerhans. Gastrinoma grows slowly but may be locally invasive; but more often it metastasizes. Due to increased gastrin production, high secretion of gastric juice with a high content of HCl and proteinases occurs, which leads to the repeated formation of peptic ulcers, especially in the duodenum, but they can also occur in the stomach, esophagus or jejunum. In 50% of cases, the patient develops diarrhea. The disease caused by excess of gastrin is called Zollinger-Ellison syndrome.
Links[edit | edit source]
Related articles[edit | edit source]
References[edit | edit source]
- POVÝŠIL, Ctibor a Ivo ŠTEINER. Special pathology. 2. edition. Prague : Galén : Karolinum, 2007. ISBN 978-80-246-1442-7.
