Oxytocin
| 'ncl. paraventricularis and ncl. supraoptic hypothalamus | |
| 9 amino acids | |
| mammary gland, uterus | |
| for G-protein coupled oxytocin (OXTR) | |
| 167050 |
Oxytocin is a peptide hormone produced in the hypothalamic nuclei (more in the nucleus paraventricularis, less in the nucleus supraopticus). The nuclei are formed by the bodies of magnocellular neurons. The axons of these neurons transport oxytocin using the transport protein ``neurophysin I to the neurohypophysis (posterior lobe of the pituitary gland), from where the hormone is released into the blood.
Effects of oxytocin
The hormone is used significantly during childbirth and during motherhood. The number of oxytocin receptors increases towards the end of pregnancy. At the beginning of birth, the release is stimulated by the dilation of the cervix. During breastfeeding, there is a pulse' release, which is a response to the irritation of the sensitive nerve endings breast gland.
Oxytocin'
- Causes contraction of the myoepithelial cells of the ducts of the mammary gland. The contraction of these cells leads to 1 min<ref name="Kittnar">{{#switch: book
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Incomplete publication citation. . Medical Physiology. Prague : Grada, 2011. 790 s. pp. 511. 978-80-7262-438-6.
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. Medical Physiology. Prague : Grada, 2011. 790 s. 978-80-7262-438-6} }, s. 511.
