Actinobacillus
Actinobacillus spp. are bacteria belonging to the family Pasteurellaceae (this further includes, for example, genera Haemophilus a Pasteurella).
Morphology[edit | edit source]
It is about gram-negative, facultatively anaerobic immobile and non-sporulating rods of pleomorphic shape, sometimes referred to as stick-like. They are often protected by a case. They can occur as sticks or coca. In media with a higher content of glucose or maltose they form fibers.
Cultivation[edit | edit source]
Actinobacillus is cultivation demanding bacteria, we inoculate it on chocolate or blood agar in an atmosphere with 5% CO2. On solid media tt forms star-shaped colonies which grow into agar, in broths we observe growth in small granules.
Occurrence[edit | edit source]
Actinobacillus spp. we find as commensal and parasitic flora mucosal tissue surfaces in humans and animals.
Clinically significant are Actinobacillus ureae and Actinobacillus hominis, which are found only in humans and can be the etiological cause of airway inflammation. Other species like Actinobacillus equuli, Actinobacillus lingieresii or Actinobacillus suis are animal pathogens that can be transmitted to humans by biting and then cause purulent infections of these wounds.
Previously Actinobacillus actinomycetemcomitans was also included in this genus, however today is ranked among the hemophiles (Haemophilus actinomycetemcomitans).
| „ | Recent studies have shown phylogenetic similarity with Haemophilus aphrophilus, Haemophilus paraprhophilus and Haemophilus segnis, as a result of these facts it has been proposed to include these bacteria together with Actinobacillus actinomycetemcomitans in the new genus Aggregatibacter .[1] | “ |
Therapy[edit | edit source]
Except penicillin, for treatment can be used most of beta-lactam antibiotics or aminoglycosides or fluoroquinolones.
Links[edit | edit source]
External links[edit | edit source]
Reference[edit | edit source]
- ↑ NØRSKOV-LAURITSEN, Niels – KILIAN, Mogens. Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter aphrophilus to include V factor-dependent and V factor-independent isolates. Int J Syst Evol Microbiol [online]. 2006, vol. 56, no. Pt 9, p. 2135-46, Available from <https://www.ncbi.nlm.nih.gov/pubmed/16957111>. ISSN 1466-5026.
Bibliography[edit | edit source]
- BEDNÁŘ, Marek. Lékařská mikrobiologie : bakteriologie, virologie, parazitologie. 1. edition. 1996.
- VOTAVA, Miroslav, et al. Lékařská mikrobiologie speciální. 1. edition. Brno : Neptun, 2003. 495 pp. ISBN 80-902896-6-5.
