Amikacin
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It is a derivative of another aminoglycoside antibiotic - kanamycin . Its indications are identical to gentamicin , but the dosage is higher. It is only used to treat infections caused by gentamicin-resistant strains.[1]
It is part of a rational antibiotic policy that says that gentamicin is the preferred antibiotic for aminoglycoside antibiotics. Only when resistant strains occur will we exchange gentamicin for amikacin. Part of the policy is also the rotation of antibiotics - the use of amikacin can, after some time, restore the pathogen's good sensitivity to gentamicin, to which it can then be returned.[2]
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- LINCOVÁ, Dagmar – FARGHALI, Hassan. Základní a aplikovaná farmakologie. 2. edition. Prague : Galén, 2007. 672 pp. ISBN 978-80-7262-373-0.
