Chromium
From WikiLectures
Biologically active is Cr3+, Cr6+ is toxic.
Function[edit | edit source]
The trivalent form of chromium is used as a glucose tolerance factor. It stimulates the action of insulin and increases glucose tolerance. It increases HDL levels in healthy people.
Conversely, professional exposure to hexavalent chromium has allergic effects and is carcinogenic.
Sources[edit | edit source]
Sources of chromium can be:
- yeast (brewer´s);
- meat;
- cheeses, wheat germ and nuts.
Recommended daily dose[edit | edit source]
The recommended daily dose of chromium is 150–200 μg.
Deficiency[edit | edit source]
Chromium deficiency can result in:
- reduced glucose tolerance to type 2 diabetes mellitus;
- hyperlipidemia;
- acceleration of atherosclerotic changes.
Toxicity[edit | edit source]
It is mainly hexavalent - it easily passes through membranes and connects DNA → DNA-DNA crosslinks – contributing to mutagenesis. It enters the body through emissions from the air and damages the respiratory tract, conjunctiva, and kidneys.
Links[edit | edit source]
Related articles[edit | edit source]
External links[edit | edit source]
Source[edit | edit source]
- BENEŠ, Jiří. Studijní materiály [online]. ©2007. [cit. 2009]. <http://www.jirben.wz.cz/>.
Used literature[edit | edit source]
- SCHNEIDERKA, Petr. Kapitoly z klinické biochemie. 2. edition. Karolinum, 2004. ISBN 80-246-0678-X.
