Cyclophosphamide
From WikiLectures
Cyclophosphamide' Template:HVLP is the main representative of oxazaphosphorine cytostatics. It is a carrier of alkylating radicals, which become active only after being metabolized in the body. It has a broad-spectrum and immunosuppressive effect. It is used orally and intravenously. Its metabolite is acrolein. It irritates the urinary tract and can cause hematuria with long-term use.
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References
- HYNIA, Sixtus. Pharmacology in a Nutshell. 2. edition. Prague : Triton, 2001. 520 pp. ISBN 80-7254-181-1.