Equianalgesic doses of opioids
From WikiLectures
The basic comparative parameter is analgesia induced by 10 mg morphine in s. c. The conversion has an indicative value and numerous inter-individual differences must be taken into account (age, nature and intensity of pain, side effects, sensitivity or tolerance to opioids, method of administration, opioid to which it is rotated). Accordingly, the appropriate dose is still adjusted.
| Morphine s. c. (i. m.) | 10 | 20 | 30 | 40 | 50 | 60 | 80 | 100 | 200 |
|---|---|---|---|---|---|---|---|---|---|
| Morphine p. o. | 30 | 60 | 90 | 120 | 150 | 180 | 240 | 300 | 600 |
| TTS fentanyl v μg / h (Durogesic) | 12.5 | 25 | — | 50 | — | 75 | 100 | 125 | 250 |
| TTS fentanyl mg/24 hours | 0.3 | 0.6 | — | 1.2 | — | 1.8 | 2.4 | 3.0 | 6.0 |
| Oxycodone p. o. (Oxycontin) | 20 (15) | 40 (30) | 60 (45) | 80 (60) | 100 (75) | 120 (90) | 160 (120) | 200 (150) | 400 |
| Buprenorphine i.m. | 0.3 | 0.6 | 0.9 | 1.2 | 1.5 | 1.8 | 2.4 | — | — |
| Buprenorphine s. l. in mg / 24 h (Temgesic) | 0.4 | 0.8 | 1.2 | 1.6 | 2.0 | 2.4 | 3.2 | — | — |
| TDS Buprenorphine v mg / 24 h (Transtec) | — | 0.84 | 1.26 | 1.68 | 2.1 | 2.52 | 3.36 | — | — |
| TDS Buprenorphine v μg / h (Transtec) | — | 35 | 52.5 | 70 | 87.5 | 105 | 140 | — | — |
| Hydromorphone i. m. (Dilaudid) | 1.5 | — | — | — | — | — | — | — | — |
| Hydromorphone p. o. (Jurnista, Palladone) | 4 | 8 | 12 | 16 | 20 | 24 | 32 | — | — |
| Pethidine – meperidine i. m. (Dolsin) | 100 (75) | — | — | — | — | — | — | — | — |
| Pethidine p. o. | 300 | — | — | — | — | — | — | — | — |
| Piritramide i. m. (Dipidolor) | 15 | 30 | 45 | — | — | — | — | — | — |
| Nalbuphine (Nubain) | 20 | — | — | — | — | — | — | — | — |
| Tramadol p. o. | 150 | 300 | 450 | 600 | — | — | — | — | — |
| Tramadol i.m./i.v. | 100 | 200 | 300 | 400 | — | — | — | — | — |
| Dihydrocodeine p. o. | 120 | 240 | 320 | — | — | — | — | — | — |
Recalculation of doses and calculation of additional doses[edit | edit source]
MediaWiki:Medical Calculator/Opioids
Links[edit | edit source]
Related Articles[edit | edit source]
- Anesthesia (pediatrics)
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- Neuroleptics (pediatrics)
- Benzodiazepines (pediatrics)
- Opioid analgesics
- Opioids (pediatrics)
Source[edit | edit source]
- Methodological guidelines for pain pharmacotherapy. In Pain - a journal for the study and treatment of pain. Volume 9, Supplement 3, 2006.
