Formulation of hypotheses
From WikiLectures
This article has been translated from WikiSkripta; the formatting needs to be checked.
Definition[edit | edit source]
- A Hypothesis is an assumption whose validity we must verify before proceeding with further scientific work.
- Provisional theory is based on descriptive research/statistics, clinical observations, analytical studies, laboratory research, theoretical modeling.[1]
Hypothesis formation methods[edit | edit source]
Differential method[edit | edit source]
- If the frequency of occurrence of a disease in two comparative populations (sets) is significantly different'' and if it is possible to identify a factor that is present in one set and not in the other, then we can label this factor as 'cause of disease.
- Example: higher incidence of ca of the cervix in married women - and vice versa lower' incidence in nuns.
Match Method[edit | edit source]
- If we can find a common factor' in a number of different populations that are characterized by the occurrence of a disease, then this factor could be the cause of the disease.
- Example: Semmelweis came to the conclusion that the cause of teenage fever was some kind of "dead poison" found 'on the hands of the attending obstetric staff.
Method of analogy[edit | edit source]
- If there are ``certain similarities in the distribution of the observed disease with another disease for which we have more complete information, it would be possible to judge that both diseases have ``some common causes. We use a deductive way of thinking.
Companion Difference Method[edit | edit source]
- The change in the frequency of the disease occurs in parallel with the change in intensity of the given factor.
- Example: incidence of lung carcinoma increases with the number of cigarettes smoked'.[2]
Links[edit | edit source]
Related Articles[edit | edit source]
- ↑ TIMMRECK, Thomas C.. An Introduction to Epidemiology. 3. edition. Sudbury : John and Bartlett Publishers, 2002. pp. 205-210. ISBN 0763700606.
- ↑ BENCKO, Vladimir, et al. Epidemiology, teaching texts for students of the 1st Faculty of Medicine UK, Prague. 2. edition. Prague : Charles University in Prague – Karolinum Publishing House, 2002. pp. 16-24. ISBN 80-246-0383-7.