Histology MCQs/Skin

St Bartholomew is often portraited without his skin.

1 What is main function of Langergans cells of epidermis?

	Antigen-presenting cells
	Mechanoreceptors
	Thermoreceptors
	Stem cells

2 Which layer of epidermis has the most intense mitotic activity?

	Basal layer
	Spinous layer
	Granular layer
	Mitotic activity is equally distributed throuhg the epidermis

3 What are keratins?

	Class of intermediate filaments in epidermis
	Class of extracellular proteins in epidermis
	Class of microfilaments in epidermis
	Class of cell adhesions in epidermis

4 Keratohyaline granules:

	They are non-membrane-bound and contain various lipids and glykolipids
	They are membrane-bound and contain various lipids and glykolipids
	They are non-membrane-bound and contain fillagrin
	They are membrane-bound and contain fillagrin

5 How many layers of keratinocytes does usually contain stratum corneum?

	15-20
	10-15
	20-25
	25-30

6 Melanin:

	Melanin is stored mainly in proximity of cell nucleus of melanocytes
	Melanin is quickly released from melanocytes to intercellular space
	Melanin is quickly transported to keratinocytes of basal layer
	Melanin is stored mainly in processes of melanocytes

7 Which aminoacid is main building block of melanin?

	Glutamine
	Tyrosine
	Proline
	Leucine

8 Which tissue is main tissue of papillary layer of dermis?

	Reticular connective tissue
	Loose connective tissue
	Dense connective tissue
	Reticular epithelium

9 Which tissue is main tissue of reticular layer of dermis?

	Reticular connective tissue
	Dense connective tissue
	Loose connective tissue
	Reticular epithelium

10 Proteoglycans of reticular layer of dermis are rich (especially) in one glycosaminoglycan. Which one?

	Chondroitin sulfate
	Dermatan sulfate
	Keratan sulfate
	Heparan sulfate

11 How is called part of the hair follicle containing vessels?

	Inner root sheat
	Dermal papilla
	Hair cuticule
	Medulla

12 Arrector pili muscle:

	It is composed of striated muscle fibers
	It is composed of striated muscle cells
	It is composed of myoepithelial cells
	It is composed of smooth muscle cells

13 Which structure is main structure of nails?

	Gamma butyric acid (GABA)
	Keratan sulfate
	Hyaluronic acid
	Keratin

14 Sebaceous glands:

	They are often associated with hair follicle
	They use merocrine type of secretion
	They are branched tubular glands
	They are abundant on palms

15 During produkci of sebum, autophagy plays an important role. What is an autophagy?

	The cell disintegrates main part of its organelles using ubiquitine-proteaseome pathway
	The cell surround part of its own cytoplasm and organells by membrane and digest it
	Autophagy is a synonym for holocrine type of secretion
	It's a trap, autophagy has nothing to do with production of sebum

16 Eccrine sweat glands are:

	Straight tubular glands
	Branched tubular glands
	Branched acinar glands
	Coiled tubular glands

17 Where are apocrine sweat glands?

	In the skin of neck
	In the axilla
	In the soles
	On the lips

18 How many vessel plexuses do we have in the dermis?

	0
	1
	2
	3

19 What is main function of pacinian corpuscle (Vater-Paccini's corpuscle)?

	Detection of pressure and vibrations
	Detection of high temperature
	Detection of low temperature
	Detection of damage

20 Which structures of the skin are often nociceptors (receptors of pain)?

	We have no receptors of pain in the skin
	Krause end-bulb bodies
	Free nerve endings
	Merkel's disks

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