Histology MCQs/Tissues of Mesenchymal Origin (2023/24)

At the Institute of H&E, we have bad experience that students prefer rather gross (macroscopic) anatomy than microscopic anatomy (histology).

1 Easter Egg: Book The Art of War (孫子兵法) written by Sun Tzu (孫子) is the oldest known book about military tactics and strategy. Which part of this book can be used for description of function of free (wondering) cells in connective tissue?

	Sun Tzu said: Whoever is first in the field and awaits the coming of the enemy, will be fresh for the fight; whoever is second in the field and has to hasten to battle will arrive exhausted.
	Sun Tzu said: The art of war is of vital importance to the State. It is a matter of life and death, a road either to safety or to ruin. Hence it is a subject of inquiry which can on no account be neglected.
	Sun Tzu said: The control of a large force is the same principle as the control of a few men: it is merely a question of dividing up their numbers.
	Sun Tzu said: We come now to the question of encamping the army, and observing signs of the enemy. Pass quickly over mountains, and keep in the neighborhood of valleys.

2 Which of following structures does not belong to fibrilary component of extracellular matrix?

	Collagen fibrils
	Collagen fibers
	Elastic fibers
	Myofibrils

3 Which molecular structure is main compound of reticular fibers?

	Type III collagen
	Type II collagen
	Serglycan
	Glycogen

4 How to stain for reticular fibers?

	Aldehyde fuscin staining
	Silver impregnation
	Sudan red staining
	Feulgen's method

5 Which of following structures is rich on reticular fibers?

	Skeletal muscle
	Compact bone
	Bone marrow
	Thymus

6 Elastic fibers are composed of two main structures. Which ones?

	Type IV collagen and chondroitin sulfate
	Type II collagen and aggrecan
	Elastin and fibrillin
	Elastin and laminin

7 Which stainig is appropriate for elastic structures?

	Methylen blue
	Alcian blue
	Sudan red
	Orcein

8 Which collagen is main collagen of collagen fibers?

	Type I collagen
	Type II collagen
	Type III collagen
	Type IV collagen

9 Which technique is appropriate for analysis of amount of connective tissue propper in the specimen?

	Any trichromatic method
	Masson's trichromes
	Mallory's trichrome
	AZAN

10 All but one of following structures are glycosaminoglycans. Which one is not?

	Chondroitin sulfate
	Heparan sulfate
	Hyaluronic acid
	Fibronectin

11 Which intracellular structure is responsible for production of sulfated glycosaminoglycans?

	Smooth endoplasmic reticulum
	Rough endoplasmic reticulum
	Golgi apparatus
	Cell membrane

12 Only one structure belongs to non-sulfated glycosaminoglycans. Which one?

	Hyaluronic acid
	Fibronectin
	Aggrecan
	Heparin

13 Do we have fixed cells of connective tissue derived from the neural crest?

	Yes, we do, for example melanocytes in meninges
	Yes, we do, for example adipocytes in mesentery
	Yes, we do, for example ostecytes in vertebrae
	No, we do not have these cells

14 Do we have fibrilary component of extracellular matrix in hyaline cartillage?

	Yes, we do, it is comosed of type II collagen fibrils
	Yes, we do, it is comosed of type IV collagen fibrils
	Yes, we do, it is comosed of type VII collagen fibrils
	No, we do not have fibrilary component in hyaline cartilage

15 Which tissue contains cells arranged in an isogenetic groups (isogenetic lineages)?

	Reticular connective tissue
	Brown adipose tissue
	Elastic cartilage
	Woven bone

16 Which scructure in brown adipocytes produces heat?

	Smooth endoplasmic reticulum
	Cytoplasmic enzymes
	Mitochondria
	Peroxisomes

17 Which of following techniques is stainig for lipids (triacylglycerols)?

	Heidenhein's hematoxylin
	Feulgen's reaction
	Sudan black
	Congo red

18 Which of following tissues is avascular?

	Loose connective tissue
	Hyaline cartilage
	Compact bone
	Tendon

19 Which type of tissuse is main tissue of ligaments?

	Dense irregular connective tissue
	Dense regular connective tissue
	Reticular connective tissue
	Fibrocartilage

20 Shape of which organ is supported by elastic cartilage?

	Outer ear
	Trachea
	Aorta
	Nose

21 Where takes place fibrocartilage?

	False ribs (costae spuria)
	Intraarticular discs
	Articular cartilage
	Nasal septum

22 Which type of collagen is main collagen of tendons?

	Type I collagen
	Type II collagen
	Type III collagen
	Type IV collagen

23 Do we have fibrilary componet of extracellular matrix in bones?

	Yes, we do. It is composed of type I collagen fibrils
	Yes, we do. It is composed of type I collagen fibers
	Yes, we do. It is composed of fibrillin fibrils
	No, we do not have it

24 How is called precursor cell of osteoclast?

	Satelite cell
	Veiled cell
	Macrophage
	Monocyte

25 Do adult people have chondroclasts (cells resorbing cartilage)?

	Yes, we do have these cells in all cartilages with exception of articular cartilages
	Yes, we do have these cells, but in healing fractures only
	Yes, we do have these cells, but in the ribs only
	No, we do not have these cells

26 Which structure composed of hyaline cartilage lacks perichondrium?

	Hyaline cartilage has perichondrium in all cases
	Cartilage covering inner surface of joins
	Cartilage on the tip of xyphoid processus
	Cartilage in the wall of trachea

27 Can we apply immunohistochemical staining on the slide obtained using cutting & grinding technique?

	Yes, we can. But we can not expect positive result, because organic structures were burned
	Yes, we can. But we can not use primary antibodies of mice origin
	Yes, we can. But we can not use DAPI system for visualization
	Yes, we can. But we can not use fluorescent dyes as label

28 Which skeletal muscle contains the longest muscle fibers?

	Extensor hallucis longus muscle
	Quadriceps femoris muscle
	Biceps brachii muscle
	Sartorius muscle

29 What is main function of tropomyosin in a skeletal muscle?

	It enhances ineraction of actin and troponin
	It prevents interaction of actin and myosin
	It acts as a receptor for calcium
	It binds troponin to myosin

30 What is immediate signal for contraction of myofibrils?

	Sharp increase of potassium level in sarcoplasma
	Sharp increase of calcium level in sarcoplasma
	Sharp drop of potassium level in sarcoplasma
	Sharp drop of calcium level in sarcoplasma

31 Is a muscle fiber of skeletal muscle a cell?

	No, it is not bounded by a cell membrane
	No, it is called syncytitum
	No, it is called coenocyt
	Yes, it is

32 What is main mediator on a neuromuscular junction of skeletal muscle?

	Acetylcholine
	Epinephrin
	Dopamine
	GABA

33 Why have smooth muscle cells no striation?

	Actin and myosin are arranged in a three-dimensional network
	They lack both actin and myosin
	They lack myosin only
	They lack actin only

34 Which cell adhesion does not take place in the intercalated disc?

	Zonula occludens
	Fascia adhaerens
	Gap junction
	Desmosome

35 Which protein acts as a ruler for length of actin filaments in sarcomeres?

	Myomesin
	Nebulin
	Actinin
	Tinin

Links

• List of all tests: Histology MCQs
• Portal:Histology