Human herpesvirus 8

Kaposis sarcoma lesions

{{Infobox - virus | name = Human herpesvirus 8 | picture = Kaposi Sarcoma Lesions.jpg | caption = Kaposi sarcoma | family = Herpesviridae | nucleic acid = dsDNA | source = human | transmission = via sexual intercourse, blood | occurrence = ubiquitous | disease = Kaposi sarcoma (HIV⁺), other malignities (angiosarcoma), [[Castleman's disease] | diagnostic = serology, detection of antibodies against nuclear antigen, HHV-8 DNA | treatment = to date there is no causal therapy available 'HHV-8' ( Human Herpesvirus 8 ), also referred to as 'KSHV' ( Kaposi sarcoma-associated herpesvirus ), is a dsDNA virus from family Herpesviridae .

• Described in patients with immune defect (HIV).
• In immunodeficiency causes Kaposi's sarcoma (mesenchymal malignant vascular tumor).
• Other diseases caused by the virus include "primary exudative lymphoma" (when malignant B-lymphoma develops) or Castleman's disease.
• It also occurs in immunocompetent persons, in whom it causes only latent infection.
• Current status diagnostics using PCR only.
• Serological diagnostics: IgG antibodies - anamnestic .

Links

Related articles

• Kaposi sarcoma

External links

• HHV8 (KHSV) – Národní referenční laboratoř pro HV

References

1. NRL pro HV. HHV8 (KHSV) [online]. [cit. 2012-01-26]. <http://www.szu.cz/uploads/documents/CeM/Herp_viry/HHV8.pdf>.

Source

• ws: https://www.wikiskripta.eu/w/HHV-8

• ŽAMPACHOVÁ, Eva. Přednášky a materiály dr. Žampachové ke stažení [online]. [cit. 2012-01-26]. <http://mujweb.cz/zampach/motol/?redirected=1521314685>.