Light's criteria
From WikiLectures
Light's criteria to help decide whether a pleural effusion nature of exudate or transudate. Total protein concentration and lactate dehydrogenase activity in punctated effusion and blood serum are assessed.
| transudate | exudate | |
|---|---|---|
| Total protein | effusion / serum < 0,5 | effusion / serum > 0,5 |
| Lactate dehydrogenase | effusion / serum < 0,6 | effusion / serum > 0,6 |
| LDH in effusion > 2/3 of the serum standard |
The physiological upper limit of the LDH standard for adult men and women is up to 4,10 µkat/l.[2]
These criteria tend to "overestimate" exudates. In controversial cases, they are therefore supplemented by so-called gradients:
- Total proteinserum − total proteineffusion > 31 g/l indicates transudate;
- Albuminserum − albumineffusion > 12 g/l indicates transudate.
References[edit | edit source]
Related Articles[edit | edit source]
References[edit | edit source]
- ↑ MAREL, Miloslav. Novinky v diferenciální diagnostice pleurálních výpotků. Zdravotnické noviny [online]. 2007, y. 56, no. 2, p. příloha Lékařské listy 23-29, Available from <https://zdravi.euro.cz/clanek/priloha-lekarske-listy/novinky-v-diferencialni-diagnostice-pleuralnich-vypotku-287450>. ISSN 1214-7664.
- ↑ Jaroslav Racek et al.: Klinická biochemie, druhé, přepracované vydání, Galén, 2006
Kategorie:Biochemie
Kategorie:Klinická biochemie
Kategorie:Pneumologie
