Lung (histology)
náhled|vpravo|Alveolo-kapilární membrána
vpravo|náhled|Mikroskopický řez, barvení HE
BT − bronchiolus terminalis
RB − respirační bronchiolus / respiratory bronchiole
AD − ductus alveolaris
A – alveolus
AS – alveolární váček / alveolar sack
IS − interalveolární septum / interalveolar septum
Under the microscope, the lungs resemble a mesh. In this case, the individual meshes of the network are formed by alveoli . The alveolus is the basic functional unit of the lungs.
On a good section, we can see the final branching of the bronchioles: Bronchioli respiratorii → Ductus alveolares → Sacculi alveolares → Alveoli. The epithelium gradually decreases - the original multi-rowed epithelium with cilia gradually becomes a single-layer cubic epithelium (bronchiole) and squamous epithelium (alveoli).
During observation, we naturally come across small vessels (max. with one to two erythrocytes in the lumen of the vessel). The cells of the epithelium of the alveoli include:
- Type I pneumocytes (small – flat – alveolar cells; organelles are gathered around the nucleus),
- Pneumocytes II. type (large – cubic – alveolar cells; microvilli; producesurfactant),
- Makrophages.
- Lymphocytes.
Alveolar septum: Capillaries, macrophages, elastic and collagen fibers, and fibroblasts are found between the two layers of type I pneumocytes.
Blood – air (alveolo – capillary) barrier:
- Type I pneumocytes..
- Basement membrane..
- Endothelial cells of capillaries.