Mental disorders caused by opioids use
From WikiLectures
Why are they taking it?[edit | edit source]
- used for their euphoric effect
- high addiction rate
Route of administration:[edit | edit source]
- IV or inhaled or snorted
Mechanism of Action:[edit | edit source]
- kappa, delta and mu-receptor agonists
- Opioid induced disorder → depressive disorder, anxiety disorder, sleep disorder, sexual dysfunction, delirium
Therapy:[edit | edit source]
- longer-acting opioid e.g. methadone, buprenorphine
- many internal comorbidities: malnutrition, infections (HIV, HCV), endocarditis, sepsis
