Myxedema Coma

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Myxedema coma is the escalation of the symptoms of hypothyroidism into a life-threatening condition.

Etiology[edit | edit source]

Untreated or poorly treated hypothyroidism + provocative moment (stress, cold, infection, injury, surgery, medication, alcohol).

Klinical picture[edit | edit source]

Diagnostics[edit | edit source]

Therapy[edit | edit source]

  • Glucocorticoids (e.g. hydrocortisone 100 mg i.v./d – current renal insufficiency cannot be excluded in most patients),
  • adjustment of water + electrolyte balance,
  • levothyroxine (200–500 μg/d gastric tube),
  • preventively antibiotics, heart failure therapy, gradual warming,
  • ALV (in respiratory insufficiency ), pacing (in severe bradycardia).


Links[edit | edit source]

Related articles[edit | edit source]

References[edit | edit source]

  • KLENER, P, et al. Vnitřní lékařství. 3. edition. Prague : Galén, 2006. ISBN 80-7262-430-X.
  • DÍTĚ, P., et al. Vnitřní lékařství. 2. edition. Prague : Galén, 2007. ISBN 978-80-7262-496-6.

References[edit | edit source]


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Kategorie:Endokrinologie Kategorie:Vnitřní lékařství