TPHA

From WikiLectures

TPHA (Treponema pallidum hemagglutination) is a syphilis screening test.

  • The antigen is T. pallidum ssp. Pallidum Nichols (so-called Nichols strain) bound to chicken erythrocytes. Agglutination occurs when this antigen meets serum antibodies.[1]
  • The sensitivity of TPHA in primary syphilis is 69-90%, in secondary syphilis 100%, and later around 97%.
  • The specificity of this test is at least 98%.[2]


Links[edit | edit source]

Related articles[edit | edit source]

References[edit | edit source]

Category: Infectious MedicineCategory: Dermatovenerology