Vascular dementia

From WikiLectures

  • brain damage by heart attacks
  • at least 100ml of tissue is damaged to cause dementia
  • with larger CMPs and smaller volume
  • mainly small arteries, thrombosis, embolism and bleeding
  • often arise suddenly and quickly, often with a history of stroke or ischemic heart disease
  • typical – fluctuating course in a short time horizon
  • the personality is preserved for a long time → they are aware of the disease for a long time → frequent depression
  • often additional neurological symptoms
  • frequent polymobility, sometimes even delirium
  • 15-30% of dementia

Vascular dementia with acute onset[edit | edit source]

  • after one more extensive heart attack, mainly in the areas of cognitive functions
  • thalamus, gyrus angularis, frontal area

Multi-infarct dementia[edit | edit source]

  • multiple small infarcts, mainly in the cortical area
  • often together with hypertension, smokers, hyperlipidemia

Subcortical vascular dementia (Binswanger's disease)[edit | edit source]

  • on the basis of hypertensive encephalopathy
  • involvement of white matter infarcts - demyelination
  • the course is different

Other types of ischemic-vascular dementias[edit | edit source]

  • sometimes status lacunaris is isolated separately – relatively mild dementia on the basis of hypertension

Diagnostics[edit | edit source]

  • the course and pre-disease, as well as the image, are important
  • risk factors - hypertension, stroke, smoking...

Therapy[edit | edit source]

  • complex as in other dementias
  • rehabilitation of intercurrent diseases - mainly hypertension, diabetes mellitus,...
  • antioxidants, nootropics…
  • additionally anticoagulants – ASA, heparin


Links[edit | edit source]

References[edit | edit source]

BENEŠ, Jiří. Studijní materiály [online]. [cit. 10.03.2010]. <http://jirben.wz.cz>.