Antidepressant intoxication

From WikiLectures

== Antidepressants ==

  • Frequent intoxication, these are substances that inhibit the reuptake of catecholamines and serotonin in the synapse, significant anticholinergic effects,
  • representatives of TCAs (tricyclic antidepressants) – imipramine' (Melipramine®), amitryptiline', dosulepin' (Prothiaden®),
    • have cardiotoxic manifestations - already at 10 times the therapeutic dose!

Clinical picture[edit | edit source]

Therapy[edit | edit source]

  • The antidote is not
  • basis of treatment – high doses of activated charcoal, care of vital functions, symptomatic therapy.

Links[edit | edit source]

Related Articles[edit | edit source]

Source[edit | edit source]


References[edit | edit source]

  • PELCLOVÁ, Daniela. Occupational diseases and intoxication. 2. edition. Prague : Karolinum, 2006. 207 pp. ISBN 80-246-1183-X.