Postradiation lung fibrosis
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Pulmonary fibrosis represents the final stage of postradiation lung changes.
- After irradiation of lung tissue with ionizing radiation at doses> 8 Gy in 30 weeks.
- Necrotic changes caused by ionizing radiation healed by a fibrotic scar.
- Clinical manifestations: dry cough, worsening dyspnea (restriction disorder with ↓ diffusion)
- Diff. dg: radiation pneumonitis (exudative alveolitis from pneumocyte + endothelial damage)
- Therapy: in small infiltrates, no treatment is necessary, in symptomatic individuals corticoids
- Risk factors: professional injury (radiologist, miner), poorly targeted radiotherapy[1]
References[edit | edit source]
Related articles[edit | edit source]
Citations[edit | edit source]
- ↑ CHILD, P., et al. Internal Medicine. 2nd edition. Prague: Galén, 2007. ISBN 978-80-7262-496-6 .
