Bacitracin
From WikiLectures
It is a topical polypeptide antibiotics, the mechanism of action of which lies in the inhibition of the formation of the bacterial wall. When applied topically, it is excellently tolerated. A small incidence of resistance is observed.
Spectrum
Includes gram positive cocci and rods.
Indication
In combination with neomycin sulphate, it forms Framycoin, of which it adds a gram-positive spectrum (neomycin acts on gram-negative microbes and staphylococci).
Side effects
They are similar to neomycin (mainly nephrotoxicity). Systemic absorption is undesirable.
Links
Related articles
Bibliography
- FARGHALI, Dagmar, et al. Základní a aplikovaná farmakologie. 2. edition. Praha : Galén, 2007. ISBN 978-80-7262-373-0.
