LSD
From WikiLectures
- A substance prepared semi-synthetically from ergot alkaloids
- Its chemical composition is lysergic acid diethylamide
- Synthesis discovered by chemist Albert Hofmann fi SANDOZ in the preparation of nikethamide in 1943
- Formerly an experimental drug in psychiatry "Delysid"
Mechanism of action[edit | edit source]
- An inhibitor of the peripheral serotonin neuronal system that regulates emotion. The mechanism is also affected by other drugs.
- LSD has an affinity for different subtypes of serotonin receptors, mainly activates 5-HT2 receptors and acts as an agonist.
Abuse[edit | edit source]
- Effective doses on absorbent pads: 25–250 µg
- Symptoms: hyperactivity, confusion, hysteria, hallucinations, delirium, dizziness
Chronic abuse[edit | edit source]
- depression, psychosis, flashbacks
- mild psychological dependence and the development of tolerance is described [1]
Links[edit | edit source]
Related articles[edit | edit source]
- Substance abuse • Drug addiction and illegal production and possession of narcotics • Opioid abuse
- Amphetamines • Cocaine • Cannabinoids • Hallucinogens •Psychopharmaceuticals • Barbiturates • Benzodiazepines • Ethanol
- Cannabinoid use disorders • Opioid use disorders
References[edit | edit source]
- ↑ BALÍKOVÁ, Marie. Abuzus a intoxikace [online]. [cit. 2012-03-09]. <https://el.lf1.cuni.cz/p56355604/>.
